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A longitudinal study of physical function in patients with early-onset dementia

Gro, Tangen; Londos, Elisabet LU ; Olsson, Johan LU and Minthon, Lennart LU (2012) In Dementia and Geriatric Cognitive Disorders Extra 2(1). p.622-631
Abstract
BACKGROUND: The aim of this study was to explore changes in mobility in terms of ambulation and transfer over 1 year in patients with early-onset Alzheimer's disease (EOAD), and to compare mobility in EOAD with patients with other types of early-onset dementia (EOOD). METHOD: Forty-two patients with EOAD and 30 patients with EOOD were included. All patients were home-dwelling and had mild or moderate

degree of dementia. Mobility was assessed using the Timed Up and Go Test (TUG), a modified version of the Clinical Outcome Variables Scale, timed stair walking, and timed rise from the floor. RESULTS: The EOAD group performed significantly better than the EOOD group on all mobility tests. After 1 year, 25 persons with EOAD were tested... (More)
BACKGROUND: The aim of this study was to explore changes in mobility in terms of ambulation and transfer over 1 year in patients with early-onset Alzheimer's disease (EOAD), and to compare mobility in EOAD with patients with other types of early-onset dementia (EOOD). METHOD: Forty-two patients with EOAD and 30 patients with EOOD were included. All patients were home-dwelling and had mild or moderate

degree of dementia. Mobility was assessed using the Timed Up and Go Test (TUG), a modified version of the Clinical Outcome Variables Scale, timed stair walking, and timed rise from the floor. RESULTS: The EOAD group performed significantly better than the EOOD group on all mobility tests. After 1 year, 25 persons with EOAD were tested again. The performance on TUG (p = 0.028) and stair walking (p =

0.02) had deteriorated at the 1-year follow-up in the EOAD group. CONCLUSION: Patients with EOAD performed better on mobility tasks than patients with EOOD, but their performance deteriorated at 1-year follow-up. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Dementia and Geriatric Cognitive Disorders Extra
volume
2
issue
1
pages
622 - 631
publisher
Karger
ISSN
1664-5464
DOI
10.1159/000345782
language
English
LU publication?
yes
id
e9430c46-46be-4f9a-a53d-1f64be26f5b6 (old id 3457872)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed?term=23341827%5Buid%5D
date added to LUP
2013-02-07 11:58:11
date last changed
2016-09-20 04:37:23
@article{e9430c46-46be-4f9a-a53d-1f64be26f5b6,
  abstract     = {BACKGROUND: The aim of this study was to explore changes in mobility in terms of ambulation and transfer over 1 year in patients with early-onset Alzheimer's disease (EOAD), and to compare mobility in EOAD with patients with other types of early-onset dementia (EOOD). METHOD: Forty-two patients with EOAD and 30 patients with EOOD were included. All patients were home-dwelling and had mild or moderate<br/><br>
degree of dementia. Mobility was assessed using the Timed Up and Go Test (TUG), a modified version of the Clinical Outcome Variables Scale, timed stair walking, and timed rise from the floor. RESULTS: The EOAD group performed significantly better than the EOOD group on all mobility tests. After 1 year, 25 persons with EOAD were tested again. The performance on TUG (p = 0.028) and stair walking (p =<br/><br>
0.02) had deteriorated at the 1-year follow-up in the EOAD group. CONCLUSION: Patients with EOAD performed better on mobility tasks than patients with EOOD, but their performance deteriorated at 1-year follow-up.},
  author       = {Gro, Tangen and Londos, Elisabet and Olsson, Johan and Minthon, Lennart},
  issn         = {1664-5464},
  language     = {eng},
  number       = {1},
  pages        = {622--631},
  publisher    = {Karger},
  series       = {Dementia and Geriatric Cognitive Disorders Extra},
  title        = {A longitudinal study of physical function in patients with early-onset dementia},
  url          = {http://dx.doi.org/10.1159/000345782},
  volume       = {2},
  year         = {2012},
}