Feasibility of semi-recumbent bicycle exercise Doppler echocardiography for the evaluation of the right heart and pulmonary circulation unit in different clinical conditions : the RIGHT heart international NETwork (RIGHT-NET)
(2021) In International Journal of Cardiovascular Imaging 37(7). p.2151-2167- Abstract
Exercise Doppler echocardiography (EDE) is a well-validated tool in ischemic and valvular heart diseases. However, its use in the assessment of the right heart and pulmonary circulation unit (RH-PCU) is limited. The aim of this study is to assess the semi-recumbent bicycle EDE feasibility for the evaluation of RH-PCU in a large multi-center population, from healthy individuals and elite athletes to patients with overt or at risk of developing pulmonary hypertension (PH). From January 2019 to July 2019, 954 subjects [mean age 54.2 ± 16.4 years, range 16-96, 430 women] underwent standardized semi-recumbent bicycle EDE with an incremental workload of 25 watts every 2 min, were prospectively enrolled among 7 centers participating to the... (More)
Exercise Doppler echocardiography (EDE) is a well-validated tool in ischemic and valvular heart diseases. However, its use in the assessment of the right heart and pulmonary circulation unit (RH-PCU) is limited. The aim of this study is to assess the semi-recumbent bicycle EDE feasibility for the evaluation of RH-PCU in a large multi-center population, from healthy individuals and elite athletes to patients with overt or at risk of developing pulmonary hypertension (PH). From January 2019 to July 2019, 954 subjects [mean age 54.2 ± 16.4 years, range 16-96, 430 women] underwent standardized semi-recumbent bicycle EDE with an incremental workload of 25 watts every 2 min, were prospectively enrolled among 7 centers participating to the RIGHT Heart International NETwork (RIGHT-NET). EDE parameters of right heart structure, function and pressures were obtained according to current recommendations. Right ventricular (RV) function at peak exercise was feasible in 903/940 (96%) by tricuspid annular plane systolic excursion (TAPSE), 667/751 (89%) by tissue Doppler-derived tricuspid lateral annular systolic velocity (S') and 445/672 (66.2%) by right ventricular fractional area change (RVFAC). RV-right atrial pressure gradient [RV-RA gradient = 4 × tricuspid regurgitation velocity2 (TRV)] was feasible in 894/954 patients (93.7%) at rest and in 816/954 (85.5%) at peak exercise. The feasibility rate in estimating pulmonary artery pressure improved to more than 95%, if both TRV and/or right ventricular outflow tract acceleration time (RVOT AcT) were considered. In high specialized echocardiography laboratories semi-recumbent bicycle EDE is a feasible tool for the assessment of the RH-PCU pressure and function.
(Less)
- author
- Ferrara, Francesco and Bossone, Eduardo
- contributor
- Ostenfeld, Ellen
LU
- author collaboration
- organization
- publishing date
- 2021-07
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Adolescent, Adult, Aged, Aged, 80 and over, Bicycling, Echocardiography, Doppler, Feasibility Studies, Female, Humans, Middle Aged, Predictive Value of Tests, Pulmonary Circulation, Ventricular Dysfunction, Right, Ventricular Function, Right, Young Adult
- in
- International Journal of Cardiovascular Imaging
- volume
- 37
- issue
- 7
- pages
- 2151 - 2167
- publisher
- Springer
- external identifiers
-
- pmid:33866467
- scopus:85106241131
- ISSN
- 1875-8312
- DOI
- 10.1007/s10554-021-02243-x
- language
- English
- LU publication?
- yes
- additional info
- © 2021. The Author(s), under exclusive licence to Springer Nature B.V.
- id
- 34a90708-0224-4967-9ec1-c6a637fbda2a
- date added to LUP
- 2022-03-16 11:11:53
- date last changed
- 2024-04-13 15:35:29
@article{34a90708-0224-4967-9ec1-c6a637fbda2a,
abstract = {{<p>Exercise Doppler echocardiography (EDE) is a well-validated tool in ischemic and valvular heart diseases. However, its use in the assessment of the right heart and pulmonary circulation unit (RH-PCU) is limited. The aim of this study is to assess the semi-recumbent bicycle EDE feasibility for the evaluation of RH-PCU in a large multi-center population, from healthy individuals and elite athletes to patients with overt or at risk of developing pulmonary hypertension (PH). From January 2019 to July 2019, 954 subjects [mean age 54.2 ± 16.4 years, range 16-96, 430 women] underwent standardized semi-recumbent bicycle EDE with an incremental workload of 25 watts every 2 min, were prospectively enrolled among 7 centers participating to the RIGHT Heart International NETwork (RIGHT-NET). EDE parameters of right heart structure, function and pressures were obtained according to current recommendations. Right ventricular (RV) function at peak exercise was feasible in 903/940 (96%) by tricuspid annular plane systolic excursion (TAPSE), 667/751 (89%) by tissue Doppler-derived tricuspid lateral annular systolic velocity (S') and 445/672 (66.2%) by right ventricular fractional area change (RVFAC). RV-right atrial pressure gradient [RV-RA gradient = 4 × tricuspid regurgitation velocity2 (TRV)] was feasible in 894/954 patients (93.7%) at rest and in 816/954 (85.5%) at peak exercise. The feasibility rate in estimating pulmonary artery pressure improved to more than 95%, if both TRV and/or right ventricular outflow tract acceleration time (RVOT AcT) were considered. In high specialized echocardiography laboratories semi-recumbent bicycle EDE is a feasible tool for the assessment of the RH-PCU pressure and function.</p>}},
author = {{Ferrara, Francesco and Bossone, Eduardo}},
issn = {{1875-8312}},
keywords = {{Adolescent; Adult; Aged; Aged, 80 and over; Bicycling; Echocardiography, Doppler; Feasibility Studies; Female; Humans; Middle Aged; Predictive Value of Tests; Pulmonary Circulation; Ventricular Dysfunction, Right; Ventricular Function, Right; Young Adult}},
language = {{eng}},
number = {{7}},
pages = {{2151--2167}},
publisher = {{Springer}},
series = {{International Journal of Cardiovascular Imaging}},
title = {{Feasibility of semi-recumbent bicycle exercise Doppler echocardiography for the evaluation of the right heart and pulmonary circulation unit in different clinical conditions : the RIGHT heart international NETwork (RIGHT-NET)}},
url = {{http://dx.doi.org/10.1007/s10554-021-02243-x}},
doi = {{10.1007/s10554-021-02243-x}},
volume = {{37}},
year = {{2021}},
}