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Human Trials of Stem Cell-Derived Dopamine Neurons for Parkinson's Disease : Dawn of a New Era

Barker, Roger A. LU ; Parmar, Malin LU orcid ; Studer, Lorenz and Takahashi, Jun (2017) In Cell Stem Cell 21(5). p.569-573
Abstract

Stem cell-based therapies for Parkinson's disease are moving into a new and exciting era, with several groups pursuing clinical trials with pluripotent stem cell (PSC)-derived dopamine neurons. As many groups have ongoing or completed GMP-level cell manufacturing, we highlight key clinical translation considerations from our recent fourth GForce-PD meeting. Stem cell-based therapies for Parkinson's disease are moving into a new and exciting era, with several groups pursuing clinical trials with pluripotent stem cell (PSC)-derived dopamine neurons. As many groups have ongoing or completed GMP-level cell manufacturing, we highlight key clinical translation considerations from our recent fourth GForce-PD meeting.

Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Cell Stem Cell
volume
21
issue
5
pages
5 pages
publisher
Cell Press
external identifiers
  • pmid:29100010
  • wos:000414251200006
  • scopus:85032947277
ISSN
1934-5909
DOI
10.1016/j.stem.2017.09.014
language
English
LU publication?
yes
id
34ec549d-4bda-4697-8896-886201516c7f
date added to LUP
2017-11-16 08:28:15
date last changed
2024-04-14 22:03:12
@misc{34ec549d-4bda-4697-8896-886201516c7f,
  abstract     = {{<p>Stem cell-based therapies for Parkinson's disease are moving into a new and exciting era, with several groups pursuing clinical trials with pluripotent stem cell (PSC)-derived dopamine neurons. As many groups have ongoing or completed GMP-level cell manufacturing, we highlight key clinical translation considerations from our recent fourth GForce-PD meeting. Stem cell-based therapies for Parkinson's disease are moving into a new and exciting era, with several groups pursuing clinical trials with pluripotent stem cell (PSC)-derived dopamine neurons. As many groups have ongoing or completed GMP-level cell manufacturing, we highlight key clinical translation considerations from our recent fourth GForce-PD meeting.</p>}},
  author       = {{Barker, Roger A. and Parmar, Malin and Studer, Lorenz and Takahashi, Jun}},
  issn         = {{1934-5909}},
  language     = {{eng}},
  month        = {{11}},
  number       = {{5}},
  pages        = {{569--573}},
  publisher    = {{Cell Press}},
  series       = {{Cell Stem Cell}},
  title        = {{Human Trials of Stem Cell-Derived Dopamine Neurons for Parkinson's Disease : Dawn of a New Era}},
  url          = {{http://dx.doi.org/10.1016/j.stem.2017.09.014}},
  doi          = {{10.1016/j.stem.2017.09.014}},
  volume       = {{21}},
  year         = {{2017}},
}