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Behavioral changes in response to feeding pancreatic-like enzymes to exocrine pancreatic insufficiency pigs.

Pierzynowski, Stefan; Swieboda, P; Filip, R; Szwiec, Katarzyna LU ; Valverde Piedra, J L; Gruijc, D; Prykhodko, Olena LU ; Fedkiv, Olexandr LU ; Kruszewska, Danuta and Botermans, J, et al. (2012) In Journal of Animal Science 90(Suppl 4). p.439-441
Abstract
Behavioral changes during pancreatic enzyme therapy have never been studied. The present study investigated behavioral changes in exocrine pancreatic insufficiency (EPI) pigs when their feed was supplemented with pancreatic-like enzymes of microbial origin. A crossover design study was used to test the effect of enzyme supplementation in 2 × 4 EPI pigs that underwent pancreatic duct ligation (PDL). After 40 d of adaptation, the study commenced, comprising 2 control and 2 enzyme feeding periods of 10 d each in sequence. On days 7 and 10 of each experimental period, behavior was monitored for 24 h and feed consumption and BW were recorded. Behavioral observations focused on the pigs' activity- lying down or passive, or sitting, or standing... (More)
Behavioral changes during pancreatic enzyme therapy have never been studied. The present study investigated behavioral changes in exocrine pancreatic insufficiency (EPI) pigs when their feed was supplemented with pancreatic-like enzymes of microbial origin. A crossover design study was used to test the effect of enzyme supplementation in 2 × 4 EPI pigs that underwent pancreatic duct ligation (PDL). After 40 d of adaptation, the study commenced, comprising 2 control and 2 enzyme feeding periods of 10 d each in sequence. On days 7 and 10 of each experimental period, behavior was monitored for 24 h and feed consumption and BW were recorded. Behavioral observations focused on the pigs' activity- lying down or passive, or sitting, or standing or active-and were expressed as percentage activity for 24 h. During the adaptation period, BW gain was completely inhibited after PDL whereas for the entire study period, the body weight increased from 10.5 ± 1.1 to 14.0 ± 1.4 kg (P < 0.01). Exocrine pancreatic insufficiency pigs were more active when fed the enzymes (21 vs. 18% per 24 h; P < 0.01). Microbial enzyme supplementation not only improved the growth of the EPI pigs but it also increased their activity. This behavior change contradicts the generally accepted norm that satiety evokes by digestion and subsequent nutrients absorption reduces human or animal motility. (Less)
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Contribution to journal
publication status
published
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in
Journal of Animal Science
volume
90
issue
Suppl 4
pages
439 - 441
publisher
American Society of Animal Science
external identifiers
  • wos:000319673100139
  • pmid:23365403
  • scopus:84882589293
ISSN
1525-3163
DOI
10.2527/jas.53868
language
English
LU publication?
yes
id
7800d425-26e9-487b-a4f2-1bf3b7266fd0 (old id 3559969)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/23365403
date added to LUP
2013-03-06 15:24:47
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2017-09-03 03:07:43
@article{7800d425-26e9-487b-a4f2-1bf3b7266fd0,
  abstract     = {Behavioral changes during pancreatic enzyme therapy have never been studied. The present study investigated behavioral changes in exocrine pancreatic insufficiency (EPI) pigs when their feed was supplemented with pancreatic-like enzymes of microbial origin. A crossover design study was used to test the effect of enzyme supplementation in 2 × 4 EPI pigs that underwent pancreatic duct ligation (PDL). After 40 d of adaptation, the study commenced, comprising 2 control and 2 enzyme feeding periods of 10 d each in sequence. On days 7 and 10 of each experimental period, behavior was monitored for 24 h and feed consumption and BW were recorded. Behavioral observations focused on the pigs' activity- lying down or passive, or sitting, or standing or active-and were expressed as percentage activity for 24 h. During the adaptation period, BW gain was completely inhibited after PDL whereas for the entire study period, the body weight increased from 10.5 ± 1.1 to 14.0 ± 1.4 kg (P &lt; 0.01). Exocrine pancreatic insufficiency pigs were more active when fed the enzymes (21 vs. 18% per 24 h; P &lt; 0.01). Microbial enzyme supplementation not only improved the growth of the EPI pigs but it also increased their activity. This behavior change contradicts the generally accepted norm that satiety evokes by digestion and subsequent nutrients absorption reduces human or animal motility.},
  author       = {Pierzynowski, Stefan and Swieboda, P and Filip, R and Szwiec, Katarzyna and Valverde Piedra, J L and Gruijc, D and Prykhodko, Olena and Fedkiv, Olexandr and Kruszewska, Danuta and Botermans, J and Svendsen, J and Skibo, G and Kovalenko, T and Osadchenko, I and Goncharova, K and Ushakova, G and Weström, Björn},
  issn         = {1525-3163},
  language     = {eng},
  number       = {Suppl 4},
  pages        = {439--441},
  publisher    = {American Society of Animal Science},
  series       = {Journal of Animal Science},
  title        = {Behavioral changes in response to feeding pancreatic-like enzymes to exocrine pancreatic insufficiency pigs.},
  url          = {http://dx.doi.org/10.2527/jas.53868},
  volume       = {90},
  year         = {2012},
}