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Immunome: a reference set of genes and proteins for systems biology of the human immune system.

Ortutay, Csaba and Vihinen, Mauno LU (2006) In Cellular Immunology 244(2). p.87-89
Abstract
The function of the immune system requires coordinated expression and action of many genes and proteins. With the emergence of high throughput technologies it has become possible to target human immunity from a systems biology point of view. To perform systems biology studies with comparable results we need not just a reference gene and protein set but also useful and descriptive reference categories for the immunity related genes. We have identified and collected the genes and proteins of the essential human immunome. The 847 genes and proteins were annotated, and characterized, and they were categorized according to their functions, protein domains and Gene Ontology terms. The reference set and the categories are freely available in the... (More)
The function of the immune system requires coordinated expression and action of many genes and proteins. With the emergence of high throughput technologies it has become possible to target human immunity from a systems biology point of view. To perform systems biology studies with comparable results we need not just a reference gene and protein set but also useful and descriptive reference categories for the immunity related genes. We have identified and collected the genes and proteins of the essential human immunome. The 847 genes and proteins were annotated, and characterized, and they were categorized according to their functions, protein domains and Gene Ontology terms. The reference set and the categories are freely available in the immunome database at http://bioinf.uta.fi/Immunome/. (Less)
Please use this url to cite or link to this publication:
author
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Immune System: physiology, Immunity: genetics
in
Cellular Immunology
volume
244
issue
2
pages
87 - 89
publisher
Elsevier
external identifiers
  • pmid:17434156
  • scopus:34248370076
ISSN
0008-8749
DOI
10.1016/j.cellimm.2007.01.012
language
English
LU publication?
no
id
c8286183-2683-4665-a3e3-c23c365b6524 (old id 3635280)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/17434156?dopt=Abstract
date added to LUP
2013-06-12 16:24:58
date last changed
2017-06-04 04:36:51
@article{c8286183-2683-4665-a3e3-c23c365b6524,
  abstract     = {The function of the immune system requires coordinated expression and action of many genes and proteins. With the emergence of high throughput technologies it has become possible to target human immunity from a systems biology point of view. To perform systems biology studies with comparable results we need not just a reference gene and protein set but also useful and descriptive reference categories for the immunity related genes. We have identified and collected the genes and proteins of the essential human immunome. The 847 genes and proteins were annotated, and characterized, and they were categorized according to their functions, protein domains and Gene Ontology terms. The reference set and the categories are freely available in the immunome database at http://bioinf.uta.fi/Immunome/.},
  author       = {Ortutay, Csaba and Vihinen, Mauno},
  issn         = {0008-8749},
  keyword      = {Immune System: physiology,Immunity: genetics},
  language     = {eng},
  number       = {2},
  pages        = {87--89},
  publisher    = {Elsevier},
  series       = {Cellular Immunology},
  title        = {Immunome: a reference set of genes and proteins for systems biology of the human immune system.},
  url          = {http://dx.doi.org/10.1016/j.cellimm.2007.01.012},
  volume       = {244},
  year         = {2006},
}