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Novel combined fluorescence/reflectance spectroscopy system for guiding brain tumor resections - hardware considerations

Xie, Zhiyuan; Xie, Haiyan LU ; Mousavi, Monirehalsadat LU ; Brydegaard, Mikkel LU ; Axelsson, Johan LU and Andersson-Engels, Stefan LU (2013) 1st International Conference on Biophotonics-Riga 9032. p.90320-90320
Abstract
Glioblastoma multiforme (GBM) has long been known as the most common and aggressive form of brain malignancy. The morphological similarities of the malignant and surrounding tissue cause difficulties to distinct the tumors during surgery. In order to achieve better results in resecting malignant brain tumors, a fiber based optical system which can be used intraoperative is developed in this project. In this context, the system hardware details, system controlling interfaces and laboratory testing results are presented. Based on the results obtained from various tests with tissue-equivalent phantoms, the system is proved to have stable performance, robust structure, and have good linearity as well as high sensitivity to low PpIX... (More)
Glioblastoma multiforme (GBM) has long been known as the most common and aggressive form of brain malignancy. The morphological similarities of the malignant and surrounding tissue cause difficulties to distinct the tumors during surgery. In order to achieve better results in resecting malignant brain tumors, a fiber based optical system which can be used intraoperative is developed in this project. In this context, the system hardware details, system controlling interfaces and laboratory testing results are presented. Based on the results obtained from various tests with tissue-equivalent phantoms, the system is proved to have stable performance, robust structure, and have good linearity as well as high sensitivity to low PpIX concentration under strong ambient light conditions. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Glioblastoma multiforme (GBM), tumor resection, PpIX fluorescence, fiber, optical probe, ambient light rejection
host publication
Biophotonics—Riga 2013 (Proceedings of SPIE)
volume
9032
pages
90320 - 90320
publisher
SPIE
conference name
1st International Conference on Biophotonics-Riga
conference location
Riga, Latvia
conference dates
2013-08-26 - 2013-08-31
external identifiers
  • wos:000328606800027
  • scopus:84891283889
ISSN
0277-786X
1996-756X
DOI
10.1117/12.2044717
language
English
LU publication?
yes
id
37ef39b0-a60b-43e2-8042-e700b924d27f (old id 4272193)
date added to LUP
2014-02-11 14:21:33
date last changed
2019-02-20 02:25:49
@inproceedings{37ef39b0-a60b-43e2-8042-e700b924d27f,
  abstract     = {Glioblastoma multiforme (GBM) has long been known as the most common and aggressive form of brain malignancy. The morphological similarities of the malignant and surrounding tissue cause difficulties to distinct the tumors during surgery. In order to achieve better results in resecting malignant brain tumors, a fiber based optical system which can be used intraoperative is developed in this project. In this context, the system hardware details, system controlling interfaces and laboratory testing results are presented. Based on the results obtained from various tests with tissue-equivalent phantoms, the system is proved to have stable performance, robust structure, and have good linearity as well as high sensitivity to low PpIX concentration under strong ambient light conditions.},
  author       = {Xie, Zhiyuan and Xie, Haiyan and Mousavi, Monirehalsadat and Brydegaard, Mikkel and Axelsson, Johan and Andersson-Engels, Stefan},
  issn         = {0277-786X},
  keyword      = {Glioblastoma multiforme (GBM),tumor resection,PpIX fluorescence,fiber,optical probe,ambient light rejection},
  language     = {eng},
  location     = {Riga, Latvia},
  pages        = {90320--90320},
  publisher    = {SPIE},
  title        = {Novel combined fluorescence/reflectance spectroscopy system for guiding brain tumor resections - hardware considerations},
  url          = {http://dx.doi.org/10.1117/12.2044717},
  volume       = {9032},
  year         = {2013},
}