Novel combined fluorescence/reflectance spectroscopy system for guiding brain tumor resections - hardware considerations
(2013) 1st International Conference on Biophotonics-Riga 9032. p.90320-90320- Abstract
- Glioblastoma multiforme (GBM) has long been known as the most common and aggressive form of brain malignancy. The morphological similarities of the malignant and surrounding tissue cause difficulties to distinct the tumors during surgery. In order to achieve better results in resecting malignant brain tumors, a fiber based optical system which can be used intraoperative is developed in this project. In this context, the system hardware details, system controlling interfaces and laboratory testing results are presented. Based on the results obtained from various tests with tissue-equivalent phantoms, the system is proved to have stable performance, robust structure, and have good linearity as well as high sensitivity to low PpIX... (More)
- Glioblastoma multiforme (GBM) has long been known as the most common and aggressive form of brain malignancy. The morphological similarities of the malignant and surrounding tissue cause difficulties to distinct the tumors during surgery. In order to achieve better results in resecting malignant brain tumors, a fiber based optical system which can be used intraoperative is developed in this project. In this context, the system hardware details, system controlling interfaces and laboratory testing results are presented. Based on the results obtained from various tests with tissue-equivalent phantoms, the system is proved to have stable performance, robust structure, and have good linearity as well as high sensitivity to low PpIX concentration under strong ambient light conditions. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4272193
- author
- Xie, Zhiyuan ; Xie, Haiyan LU ; Mousavi, Monirehalsadat LU ; Brydegaard, Mikkel LU ; Axelsson, Johan LU and Andersson-Engels, Stefan LU
- organization
- publishing date
- 2013
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- keywords
- Glioblastoma multiforme (GBM), tumor resection, PpIX fluorescence, fiber, optical probe, ambient light rejection
- host publication
- Biophotonics—Riga 2013 (Proceedings of SPIE)
- volume
- 9032
- pages
- 90320 - 90320
- publisher
- SPIE
- conference name
- 1st International Conference on Biophotonics-Riga
- conference location
- Riga, Latvia
- conference dates
- 2013-08-26 - 2013-08-31
- external identifiers
-
- wos:000328606800027
- scopus:84891283889
- ISSN
- 1996-756X
- 0277-786X
- DOI
- 10.1117/12.2044717
- language
- English
- LU publication?
- yes
- id
- 37ef39b0-a60b-43e2-8042-e700b924d27f (old id 4272193)
- date added to LUP
- 2016-04-01 10:37:22
- date last changed
- 2024-01-06 21:06:06
@inproceedings{37ef39b0-a60b-43e2-8042-e700b924d27f,
abstract = {{Glioblastoma multiforme (GBM) has long been known as the most common and aggressive form of brain malignancy. The morphological similarities of the malignant and surrounding tissue cause difficulties to distinct the tumors during surgery. In order to achieve better results in resecting malignant brain tumors, a fiber based optical system which can be used intraoperative is developed in this project. In this context, the system hardware details, system controlling interfaces and laboratory testing results are presented. Based on the results obtained from various tests with tissue-equivalent phantoms, the system is proved to have stable performance, robust structure, and have good linearity as well as high sensitivity to low PpIX concentration under strong ambient light conditions.}},
author = {{Xie, Zhiyuan and Xie, Haiyan and Mousavi, Monirehalsadat and Brydegaard, Mikkel and Axelsson, Johan and Andersson-Engels, Stefan}},
booktitle = {{Biophotonics—Riga 2013 (Proceedings of SPIE)}},
issn = {{1996-756X}},
keywords = {{Glioblastoma multiforme (GBM); tumor resection; PpIX fluorescence; fiber; optical probe; ambient light rejection}},
language = {{eng}},
pages = {{90320--90320}},
publisher = {{SPIE}},
title = {{Novel combined fluorescence/reflectance spectroscopy system for guiding brain tumor resections - hardware considerations}},
url = {{http://dx.doi.org/10.1117/12.2044717}},
doi = {{10.1117/12.2044717}},
volume = {{9032}},
year = {{2013}},
}