Outcome of Ischemic Foot Ulcer in Diabetic Patients Who Had no Invasive Vascular Intervention.
(2013) In European Journal of Vascular and Endovascular Surgery 46(1). p.110-117- Abstract
- OBJECTIVE/BACKGROUND: There is limited information regarding outcome in patients not available for revascularisation. Our aim was to identify factors related to ulcer healing in diabetic patients with severe peripheral arterial disease who were not available for revascularisation. METHODS: Diabetic patients with a foot ulcer, consecutively presenting at a multidisciplinary foot centre with systolic toe pressure <45 mmHg or an ankle pressure <80 mmHg were prospectively included. Patients who received revascularisation were excluded. All patients had continuous follow-up until healing or death. RESULTS: Out of 602 patients (median age: 76 years) included in this study, 50% healed either primarily (76%) or with a minor amputation (24%).... (More)
- OBJECTIVE/BACKGROUND: There is limited information regarding outcome in patients not available for revascularisation. Our aim was to identify factors related to ulcer healing in diabetic patients with severe peripheral arterial disease who were not available for revascularisation. METHODS: Diabetic patients with a foot ulcer, consecutively presenting at a multidisciplinary foot centre with systolic toe pressure <45 mmHg or an ankle pressure <80 mmHg were prospectively included. Patients who received revascularisation were excluded. All patients had continuous follow-up until healing or death. RESULTS: Out of 602 patients (median age: 76 years) included in this study, 50% healed either primarily (76%) or with a minor amputation (24%). Seventeen percent of patients healed after major amputation and 33% died unhealed. By regression analysis, rest pain, impaired renal function, ischemic heart disease, cerebral vascular disease, extent of tissue destruction, and ankle pressure >50 mmHg affected the outcome of the ulcers. CONCLUSION: Diabetic patients with ischemic foot ulcers not available for revascularisations are not excluded from healing without major amputation. Factors strongly related to outcome were co-morbidity, severity of peripheral arterial disease, and extent of tissue destruction. Our findings reinforce the need for a classification system considering these factors at decision-making for vascular intervention. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3804918
- author
- Elgzyri, Targ LU ; Larsson, Jan ; Thörne, Johan LU ; Eriksson, Karl-Fredrik LU and Apelqvist, Jan LU
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- in
- European Journal of Vascular and Endovascular Surgery
- volume
- 46
- issue
- 1
- pages
- 110 - 117
- publisher
- Elsevier
- external identifiers
-
- wos:000321883200020
- pmid:23642521
- scopus:84879043841
- pmid:23642521
- ISSN
- 1532-2165
- DOI
- 10.1016/j.ejvs.2013.04.013
- language
- English
- LU publication?
- yes
- id
- f899fb32-7296-4d87-afbe-059a8a9d2f37 (old id 3804918)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/23642521?dopt=Abstract
- date added to LUP
- 2016-04-01 10:59:14
- date last changed
- 2024-05-06 02:22:56
@article{f899fb32-7296-4d87-afbe-059a8a9d2f37, abstract = {{OBJECTIVE/BACKGROUND: There is limited information regarding outcome in patients not available for revascularisation. Our aim was to identify factors related to ulcer healing in diabetic patients with severe peripheral arterial disease who were not available for revascularisation. METHODS: Diabetic patients with a foot ulcer, consecutively presenting at a multidisciplinary foot centre with systolic toe pressure <45 mmHg or an ankle pressure <80 mmHg were prospectively included. Patients who received revascularisation were excluded. All patients had continuous follow-up until healing or death. RESULTS: Out of 602 patients (median age: 76 years) included in this study, 50% healed either primarily (76%) or with a minor amputation (24%). Seventeen percent of patients healed after major amputation and 33% died unhealed. By regression analysis, rest pain, impaired renal function, ischemic heart disease, cerebral vascular disease, extent of tissue destruction, and ankle pressure >50 mmHg affected the outcome of the ulcers. CONCLUSION: Diabetic patients with ischemic foot ulcers not available for revascularisations are not excluded from healing without major amputation. Factors strongly related to outcome were co-morbidity, severity of peripheral arterial disease, and extent of tissue destruction. Our findings reinforce the need for a classification system considering these factors at decision-making for vascular intervention.}}, author = {{Elgzyri, Targ and Larsson, Jan and Thörne, Johan and Eriksson, Karl-Fredrik and Apelqvist, Jan}}, issn = {{1532-2165}}, language = {{eng}}, number = {{1}}, pages = {{110--117}}, publisher = {{Elsevier}}, series = {{European Journal of Vascular and Endovascular Surgery}}, title = {{Outcome of Ischemic Foot Ulcer in Diabetic Patients Who Had no Invasive Vascular Intervention.}}, url = {{http://dx.doi.org/10.1016/j.ejvs.2013.04.013}}, doi = {{10.1016/j.ejvs.2013.04.013}}, volume = {{46}}, year = {{2013}}, }