Chronic Paronychia and Onychomadesis in Pemphigus Vegetans : An Unusual Presentation in a Rare Autoimmune Disease
(2018) In Case Reports in Medicine 2018.- Abstract
Pemphigus vegetans is a rare variant of deep acantholytic pemphigus which usually presents with vesiculobullous rash and vegetative plaques on the folds. We report a case of pemphigus vegetans patient who presented with rashes on tips of fingers and toes resembling paronychia and onychomadesis that misled the diagnosis for months. The final diagnosis of Hallopeau-type pemphigus vegetans was made based on histopathology and direct immunofluorescence studies. Interestingly, not only the clinical presentation was atypical, but blood tests for anti-desmoglein 1 and 3 antibodies by ELISA technique were also negative. Thus, the rare unusual manifestation of pemphigus vegetans in this patient may associate with different autoantibodies to... (More)
Pemphigus vegetans is a rare variant of deep acantholytic pemphigus which usually presents with vesiculobullous rash and vegetative plaques on the folds. We report a case of pemphigus vegetans patient who presented with rashes on tips of fingers and toes resembling paronychia and onychomadesis that misled the diagnosis for months. The final diagnosis of Hallopeau-type pemphigus vegetans was made based on histopathology and direct immunofluorescence studies. Interestingly, not only the clinical presentation was atypical, but blood tests for anti-desmoglein 1 and 3 antibodies by ELISA technique were also negative. Thus, the rare unusual manifestation of pemphigus vegetans in this patient may associate with different autoantibodies to desmosomal proteins compared with those of classic pemphigus patients.
(Less)
- author
- Sukakul, Thanisorn LU and Varothai, Supenya
- publishing date
- 2018
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Case Reports in Medicine
- volume
- 2018
- article number
- 5980937
- publisher
- Hindawi Limited
- external identifiers
-
- scopus:85042653342
- ISSN
- 1687-9627
- DOI
- 10.1155/2018/5980937
- language
- English
- LU publication?
- no
- additional info
- Publisher Copyright: © 2018 Thanisorn Sukakul and Supenya Varothai.
- id
- 382127bf-c2bb-4b86-90ce-5bc129e81a7c
- date added to LUP
- 2024-07-15 14:34:18
- date last changed
- 2024-07-16 13:43:55
@article{382127bf-c2bb-4b86-90ce-5bc129e81a7c, abstract = {{<p>Pemphigus vegetans is a rare variant of deep acantholytic pemphigus which usually presents with vesiculobullous rash and vegetative plaques on the folds. We report a case of pemphigus vegetans patient who presented with rashes on tips of fingers and toes resembling paronychia and onychomadesis that misled the diagnosis for months. The final diagnosis of Hallopeau-type pemphigus vegetans was made based on histopathology and direct immunofluorescence studies. Interestingly, not only the clinical presentation was atypical, but blood tests for anti-desmoglein 1 and 3 antibodies by ELISA technique were also negative. Thus, the rare unusual manifestation of pemphigus vegetans in this patient may associate with different autoantibodies to desmosomal proteins compared with those of classic pemphigus patients.</p>}}, author = {{Sukakul, Thanisorn and Varothai, Supenya}}, issn = {{1687-9627}}, language = {{eng}}, publisher = {{Hindawi Limited}}, series = {{Case Reports in Medicine}}, title = {{Chronic Paronychia and Onychomadesis in Pemphigus Vegetans : An Unusual Presentation in a Rare Autoimmune Disease}}, url = {{http://dx.doi.org/10.1155/2018/5980937}}, doi = {{10.1155/2018/5980937}}, volume = {{2018}}, year = {{2018}}, }