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Upper-body morbidity after breast cancer: incidence and evidence for evaluation, prevention, and management within a prospective surveillance model of care.

Hayes, S C; Johansson, Karin LU ; Stout, N; Prosnitz, R; Armer, J; Gabram, S and Schmitz, K H (2012) In Cancer 118(8). p.2237-2249
Abstract
The purpose of this paper is to review the incidence of upper-body morbidity (arm and breast symptoms, impairments, and lymphedema), methods for diagnosis, and prevention and treatment strategies. It was also the purpose to highlight the evidence base for integration of prospective surveillance for upper-body morbidity within standard clinical care of women with breast cancer. Between 10% and 64% of women report upper-body symptoms between 6 months and 3 years after breast cancer, and approximately 20% develop lymphedema. Symptoms remain common into longer-term survivorship, and although lymphedema may be transient for some, those who present with mild lymphedema are at increased risk of developing moderate to severe lymphedema. The... (More)
The purpose of this paper is to review the incidence of upper-body morbidity (arm and breast symptoms, impairments, and lymphedema), methods for diagnosis, and prevention and treatment strategies. It was also the purpose to highlight the evidence base for integration of prospective surveillance for upper-body morbidity within standard clinical care of women with breast cancer. Between 10% and 64% of women report upper-body symptoms between 6 months and 3 years after breast cancer, and approximately 20% develop lymphedema. Symptoms remain common into longer-term survivorship, and although lymphedema may be transient for some, those who present with mild lymphedema are at increased risk of developing moderate to severe lymphedema. The etiology of morbidity seems to be multifactorial, with the most consistent risk factors being those associated with extent of treatment. However, known risk factors cannot reliably distinguish between those who will and will not develop upper-body morbidity. Upper-body morbidity may be treatable with physical therapy. There is also evidence in support of integrating regular surveillance for upper-body morbidity into the routine care provided to women with breast cancer, with early diagnosis potentially contributing to more effective management and prevention of progression of these conditions. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Cancer
volume
118
issue
8
pages
2237 - 2249
publisher
John Wiley & Sons
external identifiers
  • wos:000302544100007
  • scopus:84859635457
ISSN
1097-0142
DOI
10.1002/cncr.27467
language
English
LU publication?
yes
id
f545bfd5-fef5-4e35-beba-16c6eb8ae6ed (old id 3916546)
date added to LUP
2013-07-02 14:25:13
date last changed
2017-11-19 04:18:16
@article{f545bfd5-fef5-4e35-beba-16c6eb8ae6ed,
  abstract     = {The purpose of this paper is to review the incidence of upper-body morbidity (arm and breast symptoms, impairments, and lymphedema), methods for diagnosis, and prevention and treatment strategies. It was also the purpose to highlight the evidence base for integration of prospective surveillance for upper-body morbidity within standard clinical care of women with breast cancer. Between 10% and 64% of women report upper-body symptoms between 6 months and 3 years after breast cancer, and approximately 20% develop lymphedema. Symptoms remain common into longer-term survivorship, and although lymphedema may be transient for some, those who present with mild lymphedema are at increased risk of developing moderate to severe lymphedema. The etiology of morbidity seems to be multifactorial, with the most consistent risk factors being those associated with extent of treatment. However, known risk factors cannot reliably distinguish between those who will and will not develop upper-body morbidity. Upper-body morbidity may be treatable with physical therapy. There is also evidence in support of integrating regular surveillance for upper-body morbidity into the routine care provided to women with breast cancer, with early diagnosis potentially contributing to more effective management and prevention of progression of these conditions.},
  author       = {Hayes, S C and Johansson, Karin and Stout, N and Prosnitz, R and Armer, J and Gabram, S and Schmitz, K H},
  issn         = {1097-0142},
  language     = {eng},
  number       = {8},
  pages        = {2237--2249},
  publisher    = {John Wiley & Sons},
  series       = {Cancer},
  title        = {Upper-body morbidity after breast cancer: incidence and evidence for evaluation, prevention, and management within a prospective surveillance model of care.},
  url          = {http://dx.doi.org/10.1002/cncr.27467},
  volume       = {118},
  year         = {2012},
}