Surgical treatment of velopharyngeal dysfunction: Incidence and associated factors in the Swedish cleft palate population
Schaar Johansson, Malin LU
; Becker, Magnus
LU
; Eriksson, Marie
; Stiernman, Mia
LU
and Klintö, Kristina
LU
(2024)
In Journal of Plastic, Reconstructive and Aesthetic Surgery
90.
p.240-248
- Abstract
- Introduction
Speech in children with cleft palate can be affected by velopharyngeal dysfunction, which persists after primary palate repair. The incidence of surgery to correct velopharyngeal dysfunction in this patient group has previously been reported as 2.6–37%. We aimed to investigate the incidence of velopharyngeal dysfunction surgery in Swedish children with cleft palate and to examine potential associations of independent variables with this incidence.
Methods
In this cohort study, we analysed data from the Swedish cleft lip and palate quality registry for 1093 children with cleft palate with or without cleft lip. Kaplan–Meier analysis was used to estimate the risk of having velopharyngeal dysfunction surgery.... (More) - Introduction
Speech in children with cleft palate can be affected by velopharyngeal dysfunction, which persists after primary palate repair. The incidence of surgery to correct velopharyngeal dysfunction in this patient group has previously been reported as 2.6–37%. We aimed to investigate the incidence of velopharyngeal dysfunction surgery in Swedish children with cleft palate and to examine potential associations of independent variables with this incidence.
Methods
In this cohort study, we analysed data from the Swedish cleft lip and palate quality registry for 1093 children with cleft palate with or without cleft lip. Kaplan–Meier analysis was used to estimate the risk of having velopharyngeal dysfunction surgery. Multivariable Cox proportional hazards models were used to estimate the associated effect of cleft subtype, additional diagnoses, gender, and age at and number of stages for primary palate repair on the primary outcome.
Results
The risk of having velopharyngeal dysfunction surgery was 25.6%. Complete primary palate repair after the age of 18 months or in more than one stage was associated with a higher risk, but it could not be determined which of these was the more significant factor. Cleft soft palate was associated with a significantly lower risk than other cleft subtypes.
Conclusions
Primary palate repair at a higher age or in more than one stage may increase the risk of having velopharyngeal dysfunction surgery. Further analysis of potential unknown confounding factors and the association between the incidence of velopharyngeal dysfunction and surgery to correct this condition is needed. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/39467fd1-5a27-46a1-bdde-4e915785a69c
- author
- Schaar Johansson, Malin
LU
; Becker, Magnus
LU
; Eriksson, Marie
; Stiernman, Mia
LU
and Klintö, Kristina
LU
- organization
- publishing date
- 2024-02-02
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Plastic, Reconstructive and Aesthetic Surgery
- volume
- 90
- pages
- 240 - 248
- publisher
- Elsevier
- external identifiers
-
- pmid:38387421
- scopus:85186066824
- ISSN
- 1878-0539
- DOI
- 10.1016/j.bjps.2024.01.034
- language
- English
- LU publication?
- yes
- id
- 39467fd1-5a27-46a1-bdde-4e915785a69c
- date added to LUP
- 2024-03-01 14:50:38
- date last changed
- 2024-03-26 15:19:10
@article{39467fd1-5a27-46a1-bdde-4e915785a69c,
abstract = {{Introduction<br/>Speech in children with cleft palate can be affected by velopharyngeal dysfunction, which persists after primary palate repair. The incidence of surgery to correct velopharyngeal dysfunction in this patient group has previously been reported as 2.6–37%. We aimed to investigate the incidence of velopharyngeal dysfunction surgery in Swedish children with cleft palate and to examine potential associations of independent variables with this incidence.<br/><br/>Methods<br/>In this cohort study, we analysed data from the Swedish cleft lip and palate quality registry for 1093 children with cleft palate with or without cleft lip. Kaplan–Meier analysis was used to estimate the risk of having velopharyngeal dysfunction surgery. Multivariable Cox proportional hazards models were used to estimate the associated effect of cleft subtype, additional diagnoses, gender, and age at and number of stages for primary palate repair on the primary outcome.<br/><br/>Results<br/>The risk of having velopharyngeal dysfunction surgery was 25.6%. Complete primary palate repair after the age of 18 months or in more than one stage was associated with a higher risk, but it could not be determined which of these was the more significant factor. Cleft soft palate was associated with a significantly lower risk than other cleft subtypes.<br/><br/>Conclusions<br/>Primary palate repair at a higher age or in more than one stage may increase the risk of having velopharyngeal dysfunction surgery. Further analysis of potential unknown confounding factors and the association between the incidence of velopharyngeal dysfunction and surgery to correct this condition is needed.}},
author = {{Schaar Johansson, Malin and Becker, Magnus and Eriksson, Marie and Stiernman, Mia and Klintö, Kristina}},
issn = {{1878-0539}},
language = {{eng}},
month = {{02}},
pages = {{240--248}},
publisher = {{Elsevier}},
series = {{Journal of Plastic, Reconstructive and Aesthetic Surgery}},
title = {{Surgical treatment of velopharyngeal dysfunction: Incidence and associated factors in the Swedish cleft palate population}},
url = {{http://dx.doi.org/10.1016/j.bjps.2024.01.034}},
doi = {{10.1016/j.bjps.2024.01.034}},
volume = {{90}},
year = {{2024}},
}