A two-dimensional model for stress driven diffusion in bone tissue.
Lindberg, Gustav LU
; Banks-Sills, Leslie
LU
; Ståhle, Per
LU
and Svensson, Ingrid
LU
(2015)
In Computer Methods in Biomechanics and Biomedical Engineering
18(5).
p.457-467
- Abstract
- The growth and resorption of bone are governed by interaction between several cells such as bone-forming osteoblasts, osteocytes, lining cells and bone-resorbing osteoclasts. The cells considered in this study reside in the periosteum. Furthermore, they are believed to be activated by certain substances to initiate bone growth. This study focuses on the role that stress driven diffusion plays in the transport of these substances from the medullary cavity to the periosteum. Calculations of stress driven diffusion are performed under steady state conditions using a finite element method with the concentration of nutrients in the cambium layer of the periosteum obtained for different choices of load frequencies. The results are compared with... (More)
- The growth and resorption of bone are governed by interaction between several cells such as bone-forming osteoblasts, osteocytes, lining cells and bone-resorbing osteoclasts. The cells considered in this study reside in the periosteum. Furthermore, they are believed to be activated by certain substances to initiate bone growth. This study focuses on the role that stress driven diffusion plays in the transport of these substances from the medullary cavity to the periosteum. Calculations of stress driven diffusion are performed under steady state conditions using a finite element method with the concentration of nutrients in the cambium layer of the periosteum obtained for different choices of load frequencies. The results are compared with experimental findings, suggesting that increased bone growth occurs in the neighbourhood of relatively high nutrient concentration. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3955807
- author
- Lindberg, Gustav
LU
; Banks-Sills, Leslie
LU
; Ståhle, Per
LU
and Svensson, Ingrid
LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- bone growth, diffusion, stress enhanced, finite element method, steady-state, periosteal membrane
- in
- Computer Methods in Biomechanics and Biomedical Engineering
- volume
- 18
- issue
- 5
- pages
- 10 pages
- publisher
- Taylor & Francis
- external identifiers
-
- pmid:23865643
- wos:000345142700001
- scopus:84911990109
- pmid:23865643
- ISSN
- 1025-5842
- DOI
- 10.1080/10255842.2013.807507
- language
- English
- LU publication?
- yes
- id
- c3c631ab-628b-40ea-a5bc-f64e1cb10d2e (old id 3955807)
- date added to LUP
- 2016-04-01 10:49:37
- date last changed
- 2022-01-26 02:49:45
@article{c3c631ab-628b-40ea-a5bc-f64e1cb10d2e,
abstract = {{The growth and resorption of bone are governed by interaction between several cells such as bone-forming osteoblasts, osteocytes, lining cells and bone-resorbing osteoclasts. The cells considered in this study reside in the periosteum. Furthermore, they are believed to be activated by certain substances to initiate bone growth. This study focuses on the role that stress driven diffusion plays in the transport of these substances from the medullary cavity to the periosteum. Calculations of stress driven diffusion are performed under steady state conditions using a finite element method with the concentration of nutrients in the cambium layer of the periosteum obtained for different choices of load frequencies. The results are compared with experimental findings, suggesting that increased bone growth occurs in the neighbourhood of relatively high nutrient concentration.}},
author = {{Lindberg, Gustav and Banks-Sills, Leslie and Ståhle, Per and Svensson, Ingrid}},
issn = {{1025-5842}},
keywords = {{bone growth; diffusion; stress enhanced; finite element method; steady-state; periosteal membrane}},
language = {{eng}},
number = {{5}},
pages = {{457--467}},
publisher = {{Taylor & Francis}},
series = {{Computer Methods in Biomechanics and Biomedical Engineering}},
title = {{A two-dimensional model for stress driven diffusion in bone tissue.}},
url = {{http://dx.doi.org/10.1080/10255842.2013.807507}},
doi = {{10.1080/10255842.2013.807507}},
volume = {{18}},
year = {{2015}},
}