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Value of gadolinium in brain MRI examinations for developmental delay

Foerster, Bradley R. ; Ksar, Jamal ; Petrou, Myria ; Eldevik, Petr O. ; Maly, Pavel LU ; Carlson, Martha D. and Sundgren, Pia C. (2006) In Pediatric Neurology 35(2). p.126-130
Abstract
The aim of this study was to evaluate the added utility of gadolinium administration in the magnetic resonance imaging evaluation of developmental delay in children less than 2 years of age. A computerized retrospective study identified all brain magnetic resonance imaging examinations using gadolinium performed at our institution from 1995-2002 for children under the age of 2 years. Review of the clinical records and magnetic resonance imaging reports identified 170 brain magnetic resonance imaging examinations that were performed for developmental delay. Magnetic resonance imaging studies with enhancing lesions were reviewed by two staff neuroradiologists and two radiology residents. Contrast administration was rated as essential,... (More)
The aim of this study was to evaluate the added utility of gadolinium administration in the magnetic resonance imaging evaluation of developmental delay in children less than 2 years of age. A computerized retrospective study identified all brain magnetic resonance imaging examinations using gadolinium performed at our institution from 1995-2002 for children under the age of 2 years. Review of the clinical records and magnetic resonance imaging reports identified 170 brain magnetic resonance imaging examinations that were performed for developmental delay. Magnetic resonance imaging studies with enhancing lesions were reviewed by two staff neuroradiologists and two radiology residents. Contrast administration was rated as essential, helpful, or not helpful for each study. In the 107 patients in whom developmental delay was the primary concern, there were no cases in which the findings would have been missed without gadolinium administration. In the 63 patients in whom developmental delay was a secondary concern, there were several cases (11%) where contrast was helpful but not essential in reaching a radiologic diagnosis. In conclusion, intravenous gadolinium has an extremely low yield in children under the age of 2 where developmental delay is the primary concern. In young children for whom developmental delay is a secondary concern, we advocate the use of gadolinium particularly where tumor or infection is clinically suspected. (c) 2006 by Elsevier Inc. All rights reserved. (Less)
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author
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organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Pediatric Neurology
volume
35
issue
2
pages
126 - 130
publisher
Elsevier
external identifiers
  • wos:000239697900009
  • pmid:16876010
  • scopus:33746198198
ISSN
0887-8994
DOI
10.1016/j.pediatrneurol.2006.02.014
language
English
LU publication?
yes
id
76a74109-ac85-4a9d-a776-219ab86b9545 (old id 398248)
date added to LUP
2016-04-01 12:23:32
date last changed
2020-11-24 03:57:08
@article{76a74109-ac85-4a9d-a776-219ab86b9545,
  abstract     = {The aim of this study was to evaluate the added utility of gadolinium administration in the magnetic resonance imaging evaluation of developmental delay in children less than 2 years of age. A computerized retrospective study identified all brain magnetic resonance imaging examinations using gadolinium performed at our institution from 1995-2002 for children under the age of 2 years. Review of the clinical records and magnetic resonance imaging reports identified 170 brain magnetic resonance imaging examinations that were performed for developmental delay. Magnetic resonance imaging studies with enhancing lesions were reviewed by two staff neuroradiologists and two radiology residents. Contrast administration was rated as essential, helpful, or not helpful for each study. In the 107 patients in whom developmental delay was the primary concern, there were no cases in which the findings would have been missed without gadolinium administration. In the 63 patients in whom developmental delay was a secondary concern, there were several cases (11%) where contrast was helpful but not essential in reaching a radiologic diagnosis. In conclusion, intravenous gadolinium has an extremely low yield in children under the age of 2 where developmental delay is the primary concern. In young children for whom developmental delay is a secondary concern, we advocate the use of gadolinium particularly where tumor or infection is clinically suspected. (c) 2006 by Elsevier Inc. All rights reserved.},
  author       = {Foerster, Bradley R. and Ksar, Jamal and Petrou, Myria and Eldevik, Petr O. and Maly, Pavel and Carlson, Martha D. and Sundgren, Pia C.},
  issn         = {0887-8994},
  language     = {eng},
  number       = {2},
  pages        = {126--130},
  publisher    = {Elsevier},
  series       = {Pediatric Neurology},
  title        = {Value of gadolinium in brain MRI examinations for developmental delay},
  url          = {http://dx.doi.org/10.1016/j.pediatrneurol.2006.02.014},
  doi          = {10.1016/j.pediatrneurol.2006.02.014},
  volume       = {35},
  year         = {2006},
}