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A clinical case series of six extremely aggressive youths treated with olanzapine

Söderström, Henrik LU ; Råstam, Maria LU orcid and Gillberg, Christopher (2002) In European Child & Adolescent Psychiatry 11(3). p.138-141
Abstract
Olanzapine is an atypical neuroleptic drug with mood-stabilising properties and few of the side effects commonly associated with conventional neuroleptic treatment. We used olanzapine, 5-20 mg/day, to treat severe aggression in six non-psychotic teenage boys with neuropsychiatric disorders. All but one started to respond within one week. The therapeutic effect in four of the patients clearly outweighed the side effects (weight gain and sedation). The subjects described a markedly increased sense of well being during the olanzapine treatment.
Please use this url to cite or link to this publication:
author
; and
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Olanzapine, violence, aggression, adolescents, neuropsychiatry
in
European Child & Adolescent Psychiatry
volume
11
issue
3
pages
138 - 141
publisher
Springer
external identifiers
  • pmid:12369774
  • scopus:0036381504
ISSN
1435-165X
DOI
10.1007/s00787-002-0265-3
language
English
LU publication?
no
id
3c89665f-b4af-4e69-bc92-0700c8eee474 (old id 1124034)
date added to LUP
2016-04-01 16:53:10
date last changed
2022-03-22 21:51:43
@article{3c89665f-b4af-4e69-bc92-0700c8eee474,
  abstract     = {{Olanzapine is an atypical neuroleptic drug with mood-stabilising properties and few of the side effects commonly associated with conventional neuroleptic treatment. We used olanzapine, 5-20 mg/day, to treat severe aggression in six non-psychotic teenage boys with neuropsychiatric disorders. All but one started to respond within one week. The therapeutic effect in four of the patients clearly outweighed the side effects (weight gain and sedation). The subjects described a markedly increased sense of well being during the olanzapine treatment.}},
  author       = {{Söderström, Henrik and Råstam, Maria and Gillberg, Christopher}},
  issn         = {{1435-165X}},
  keywords     = {{Olanzapine; violence; aggression; adolescents; neuropsychiatry}},
  language     = {{eng}},
  number       = {{3}},
  pages        = {{138--141}},
  publisher    = {{Springer}},
  series       = {{European Child & Adolescent Psychiatry}},
  title        = {{A clinical case series of six extremely aggressive youths treated with olanzapine}},
  url          = {{http://dx.doi.org/10.1007/s00787-002-0265-3}},
  doi          = {{10.1007/s00787-002-0265-3}},
  volume       = {{11}},
  year         = {{2002}},
}