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Outcome from spontaneous subarachnoid haemorrhage--results from 2007-2011 and comparison with our previous series

Ronne-Engström, Elisabeth; Borota, Ljubisa; Kothimbakam, Raj; Marklund, Niklas LU ; Lewén, Anders and Enblad, Per (2014) In Upsala Journal of Medical Sciences 119(1). p.38-43
Abstract

OBJECTIVES: The management of patients with spontaneous subarachnoid haemorrhage (SAH) has changed, in part due to interventions now being extended to patients who are older and in a worse clinical condition. This study evaluates the effects of these changes on a complete 5-year patient material.

METHODS: Demographic data and results from 615 patients with SAH admitted from 2007 to 2011 were put together. Aneurysms were found in 448 patients (72.8%). They were compared with the aneurysm group (n = 676) from a previously published series from our centre (2001-2006). Linear regression was used to determine variables predicting functional outcome in the whole aneurysm group (2001-2011).

RESULTS: Patients in the more recent... (More)

OBJECTIVES: The management of patients with spontaneous subarachnoid haemorrhage (SAH) has changed, in part due to interventions now being extended to patients who are older and in a worse clinical condition. This study evaluates the effects of these changes on a complete 5-year patient material.

METHODS: Demographic data and results from 615 patients with SAH admitted from 2007 to 2011 were put together. Aneurysms were found in 448 patients (72.8%). They were compared with the aneurysm group (n = 676) from a previously published series from our centre (2001-2006). Linear regression was used to determine variables predicting functional outcome in the whole aneurysm group (2001-2011).

RESULTS: Patients in the more recent aneurysm group were older, and they were in a worse clinical condition on admission. Regarding younger patients admitted in World Federation of Neurosurgical Societies SAH grading (WFNS) 3, there were fewer with a good outcome. In the whole aneurysm group 2001-2011, outcome was best predicted by age, clinical condition at admission, and the size of the bleeding, and not by treatment mode or localization of aneurysm.

CONCLUSION: It seems important for the outcome that aneurysms are treated early. The clinical course after that depends largely on the condition of the patient on admission rather than on aneurysm treatment method. This, together with the fact that older patients and those in worse condition are now being admitted, increases demands on neurointensive care. Further improvement in patient outcome depends on better understanding of acute brain injury mechanisms and improved neurointensive care as well as rehabilitation measures.

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author
organization
publishing date
type
Contribution to journal
publication status
published
keywords
Aged, Angiography, Female, Humans, Male, Middle Aged, Subarachnoid Hemorrhage, Tomography, X-Ray Computed, Treatment Outcome, Comparative Study, Journal Article
in
Upsala Journal of Medical Sciences
volume
119
issue
1
pages
38 - 43
publisher
Taylor & Francis
external identifiers
  • scopus:84894036744
ISSN
0300-9734
DOI
10.3109/03009734.2013.849781
language
English
LU publication?
no
id
3d8d00b7-3b29-4053-a5d3-23cda9398d2e
date added to LUP
2018-03-04 12:00:07
date last changed
2019-11-05 04:49:34
@article{3d8d00b7-3b29-4053-a5d3-23cda9398d2e,
  abstract     = {<p>OBJECTIVES: The management of patients with spontaneous subarachnoid haemorrhage (SAH) has changed, in part due to interventions now being extended to patients who are older and in a worse clinical condition. This study evaluates the effects of these changes on a complete 5-year patient material.</p><p>METHODS: Demographic data and results from 615 patients with SAH admitted from 2007 to 2011 were put together. Aneurysms were found in 448 patients (72.8%). They were compared with the aneurysm group (n = 676) from a previously published series from our centre (2001-2006). Linear regression was used to determine variables predicting functional outcome in the whole aneurysm group (2001-2011).</p><p>RESULTS: Patients in the more recent aneurysm group were older, and they were in a worse clinical condition on admission. Regarding younger patients admitted in World Federation of Neurosurgical Societies SAH grading (WFNS) 3, there were fewer with a good outcome. In the whole aneurysm group 2001-2011, outcome was best predicted by age, clinical condition at admission, and the size of the bleeding, and not by treatment mode or localization of aneurysm.</p><p>CONCLUSION: It seems important for the outcome that aneurysms are treated early. The clinical course after that depends largely on the condition of the patient on admission rather than on aneurysm treatment method. This, together with the fact that older patients and those in worse condition are now being admitted, increases demands on neurointensive care. Further improvement in patient outcome depends on better understanding of acute brain injury mechanisms and improved neurointensive care as well as rehabilitation measures.</p>},
  author       = {Ronne-Engström, Elisabeth and Borota, Ljubisa and Kothimbakam, Raj and Marklund, Niklas and Lewén, Anders and Enblad, Per},
  issn         = {0300-9734},
  keyword      = {Aged,Angiography,Female,Humans,Male,Middle Aged,Subarachnoid Hemorrhage,Tomography, X-Ray Computed,Treatment Outcome,Comparative Study,Journal Article},
  language     = {eng},
  number       = {1},
  pages        = {38--43},
  publisher    = {Taylor & Francis},
  series       = {Upsala Journal of Medical Sciences},
  title        = {Outcome from spontaneous subarachnoid haemorrhage--results from 2007-2011 and comparison with our previous series},
  url          = {http://dx.doi.org/10.3109/03009734.2013.849781},
  volume       = {119},
  year         = {2014},
}