Empirical Bayes and semi-Bayes adjustments for a vast number of estimations.
(2009) In European Journal of Epidemiology 24. p.737-741- Abstract
- Investigators in modern molecular/genetic epidemiology studies commonly analyze data on a vast number of candidate genetic markers. In such situations, rather than conventional estimation of effects (odds ratios), more accurate estimation methods are needed. The author proposes consideration of empirical Bayes and semi-Bayes methods, which yield 'adjustments for multiple estimations' by shrinking conventional effect estimates towards the overall average effect.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1500482
- author
- Strömberg, Ulf LU
- organization
- publishing date
- 2009
- type
- Contribution to journal
- publication status
- published
- subject
- in
- European Journal of Epidemiology
- volume
- 24
- pages
- 737 - 741
- publisher
- Springer
- external identifiers
-
- wos:000272615500005
- pmid:19813100
- scopus:73449086937
- pmid:19813100
- ISSN
- 1573-7284
- DOI
- 10.1007/s10654-009-9393-0
- language
- English
- LU publication?
- yes
- id
- 3dc1b5e6-9013-44ff-bd39-1f8ea7a55556 (old id 1500482)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/19813100?dopt=Abstract
- date added to LUP
- 2016-04-04 07:45:51
- date last changed
- 2025-04-04 15:06:03
@article{3dc1b5e6-9013-44ff-bd39-1f8ea7a55556, abstract = {{Investigators in modern molecular/genetic epidemiology studies commonly analyze data on a vast number of candidate genetic markers. In such situations, rather than conventional estimation of effects (odds ratios), more accurate estimation methods are needed. The author proposes consideration of empirical Bayes and semi-Bayes methods, which yield 'adjustments for multiple estimations' by shrinking conventional effect estimates towards the overall average effect.}}, author = {{Strömberg, Ulf}}, issn = {{1573-7284}}, language = {{eng}}, pages = {{737--741}}, publisher = {{Springer}}, series = {{European Journal of Epidemiology}}, title = {{Empirical Bayes and semi-Bayes adjustments for a vast number of estimations.}}, url = {{http://dx.doi.org/10.1007/s10654-009-9393-0}}, doi = {{10.1007/s10654-009-9393-0}}, volume = {{24}}, year = {{2009}}, }