How to manage invasive procedures in children with haemophilia.
Ljung, Rolf LU
and Knobe, Karin
LU
(2012)
In British Journal of Haematology
157(5).
p.519-528
- Abstract
- Invasive procedures can be performed safely in children with haemophilia due to the availability of factor VIII/IX for patients without inhibitors. Most guidelines are based on the experiences in adults, but still there is no established consensus on the optimal factor levels or duration of replacement therapy for adults undergoing surgery. Few publications have focused on surgery in children with haemophilia. Children who have developed inhibitors to factor VIII/IX have to be treated with bypassing agents and constitute a group at higher risk for bleeding complications during surgery. The aim of this review is to summarize the experiences and opinions in the literature on replacement treatment of children with haemophilia, with and... (More)
- Invasive procedures can be performed safely in children with haemophilia due to the availability of factor VIII/IX for patients without inhibitors. Most guidelines are based on the experiences in adults, but still there is no established consensus on the optimal factor levels or duration of replacement therapy for adults undergoing surgery. Few publications have focused on surgery in children with haemophilia. Children who have developed inhibitors to factor VIII/IX have to be treated with bypassing agents and constitute a group at higher risk for bleeding complications during surgery. The aim of this review is to summarize the experiences and opinions in the literature on replacement treatment of children with haemophilia, with and without inhibitors, during and after surgery, with a focus on the most prevalent clinical situations. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2432268
- author
- Ljung, Rolf
LU
and Knobe, Karin
LU
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- in
- British Journal of Haematology
- volume
- 157
- issue
- 5
- pages
- 519 - 528
- publisher
- Wiley-Blackwell
- external identifiers
-
- wos:000303856400003
- pmid:22390160
- scopus:84860840887
- ISSN
- 0007-1048
- DOI
- 10.1111/j.1365-2141.2012.09089.x
- language
- English
- LU publication?
- yes
- id
- 3fa79be4-16c3-439e-b642-6c5a286541c2 (old id 2432268)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/22390160?dopt=Abstract
- date added to LUP
- 2016-04-04 07:44:06
- date last changed
- 2022-07-24 18:33:56
@article{3fa79be4-16c3-439e-b642-6c5a286541c2,
abstract = {{Invasive procedures can be performed safely in children with haemophilia due to the availability of factor VIII/IX for patients without inhibitors. Most guidelines are based on the experiences in adults, but still there is no established consensus on the optimal factor levels or duration of replacement therapy for adults undergoing surgery. Few publications have focused on surgery in children with haemophilia. Children who have developed inhibitors to factor VIII/IX have to be treated with bypassing agents and constitute a group at higher risk for bleeding complications during surgery. The aim of this review is to summarize the experiences and opinions in the literature on replacement treatment of children with haemophilia, with and without inhibitors, during and after surgery, with a focus on the most prevalent clinical situations.}},
author = {{Ljung, Rolf and Knobe, Karin}},
issn = {{0007-1048}},
language = {{eng}},
number = {{5}},
pages = {{519--528}},
publisher = {{Wiley-Blackwell}},
series = {{British Journal of Haematology}},
title = {{How to manage invasive procedures in children with haemophilia.}},
url = {{http://dx.doi.org/10.1111/j.1365-2141.2012.09089.x}},
doi = {{10.1111/j.1365-2141.2012.09089.x}},
volume = {{157}},
year = {{2012}},
}