Advanced

Individual whole-body concentration of (137)Cesium is associated with decreased blood counts in children in the Chernobyl-contaminated areas, Ukraine, 2008-2010.

Lindgren, Anna LU ; Stepanova, Eugenia; Vdovenko, Vitaliy; McMahon, Daria; Litvinetz, Oksana; Leonovich, Elena and Karmaus, Wilfried (2015) In Journal of Exposure Science & Environmental Epidemiology 25(3). p.334-342
Abstract
The Narodichesky region, Zhitomir Oblast, Ukraine, is situated ∼80 km from the Chernobyl Nuclear Power Plant, which exploded in 1986 and polluted the environment. A previous study found that children living in villages with high activity of (137)Cesium (Cs) in the soil had decreased levels of hemoglobin, erythrocytes and thrombocytes. These findings motivated the present study that used a more comprehensive exposure assessment, including individual whole-body concentrations (WBC) of (137)Cs (Bq/kg). This cross-sectional sample examined between 2008-2010, included 590 children in the age 0-18 years. Children with higher individual log(WBC) activity in the body had significantly decreased hemoglobin, erythrocyte and thrombocyte counts. The... (More)
The Narodichesky region, Zhitomir Oblast, Ukraine, is situated ∼80 km from the Chernobyl Nuclear Power Plant, which exploded in 1986 and polluted the environment. A previous study found that children living in villages with high activity of (137)Cesium (Cs) in the soil had decreased levels of hemoglobin, erythrocytes and thrombocytes. These findings motivated the present study that used a more comprehensive exposure assessment, including individual whole-body concentrations (WBC) of (137)Cs (Bq/kg). This cross-sectional sample examined between 2008-2010, included 590 children in the age 0-18 years. Children with higher individual log(WBC) activity in the body had significantly decreased hemoglobin, erythrocyte and thrombocyte counts. The effect of log(WBC) on decreased thrombocyte count was only seen in children older than 12 years. The average village activity of (137)Cs (kBq/m(2)) in soil was associated with decreased blood counts only indirectly, through (137)Cs in the body as an intermediate variable. Children in this study were born at least 4 years after the accident and thus exposed to low doses of ionizing radiation from (137)Cs. This cross-sectional study indicates that low levels may be associated with decreased blood counts, but we cannot exclude that these results are due to residual confounding factors.Journal of Exposure Science and Environmental Epidemiology advance online publication, 25 September 2013; doi:10.1038/jes.2013.60. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Exposure Science & Environmental Epidemiology
volume
25
issue
3
pages
334 - 342
publisher
Nature Publishing Group
external identifiers
  • pmid:24064533
  • wos:000353405500014
  • scopus:84928586257
ISSN
1559-064X
DOI
10.1038/jes.2013.60
language
English
LU publication?
yes
id
d6495a71-3aa0-4d00-a767-480d1c6af436 (old id 4065388)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24064533?dopt=Abstract
date added to LUP
2013-10-03 22:06:59
date last changed
2017-09-24 03:25:21
@article{d6495a71-3aa0-4d00-a767-480d1c6af436,
  abstract     = {The Narodichesky region, Zhitomir Oblast, Ukraine, is situated ∼80 km from the Chernobyl Nuclear Power Plant, which exploded in 1986 and polluted the environment. A previous study found that children living in villages with high activity of (137)Cesium (Cs) in the soil had decreased levels of hemoglobin, erythrocytes and thrombocytes. These findings motivated the present study that used a more comprehensive exposure assessment, including individual whole-body concentrations (WBC) of (137)Cs (Bq/kg). This cross-sectional sample examined between 2008-2010, included 590 children in the age 0-18 years. Children with higher individual log(WBC) activity in the body had significantly decreased hemoglobin, erythrocyte and thrombocyte counts. The effect of log(WBC) on decreased thrombocyte count was only seen in children older than 12 years. The average village activity of (137)Cs (kBq/m(2)) in soil was associated with decreased blood counts only indirectly, through (137)Cs in the body as an intermediate variable. Children in this study were born at least 4 years after the accident and thus exposed to low doses of ionizing radiation from (137)Cs. This cross-sectional study indicates that low levels may be associated with decreased blood counts, but we cannot exclude that these results are due to residual confounding factors.Journal of Exposure Science and Environmental Epidemiology advance online publication, 25 September 2013; doi:10.1038/jes.2013.60.},
  author       = {Lindgren, Anna and Stepanova, Eugenia and Vdovenko, Vitaliy and McMahon, Daria and Litvinetz, Oksana and Leonovich, Elena and Karmaus, Wilfried},
  issn         = {1559-064X},
  language     = {eng},
  number       = {3},
  pages        = {334--342},
  publisher    = {Nature Publishing Group},
  series       = {Journal of Exposure Science & Environmental Epidemiology},
  title        = {Individual whole-body concentration of (137)Cesium is associated with decreased blood counts in children in the Chernobyl-contaminated areas, Ukraine, 2008-2010.},
  url          = {http://dx.doi.org/10.1038/jes.2013.60},
  volume       = {25},
  year         = {2015},
}