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Plasma levels of high-sensitive C-reactive protein do not correlate with inflammatory activity in carotid atherosclerotic plaques.

Grufman, Helena LU ; Goncalves, Isabel LU ; Edsfeldt, Andreas LU ; Nitulescu, Mihaela LU ; Persson, Ana LU ; Nilsson, Marie MN LU and Nilsson, Jan LU (2014) In Journal of Internal Medicine 275(2). p.127-133
Abstract
It is well established that subjects with moderately elevated plasma levels of C-reactive protein (CRP) have an increased risk of development of cardiovascular events. As atherosclerosis is a disease characterized by chronic arterial inflammation, it is possible that moderate increases in CRP level reflect the presence of plaque inflammation. To investigate this possibility we compared plasma levels of hsCRP the day before carotid endarterectomy with the degree of inflammation in the excised plaque tissue.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Internal Medicine
volume
275
issue
2
pages
127 - 133
publisher
Wiley-Blackwell Publishing Ltd
external identifiers
  • wos:000329764500004
  • pmid:24010553
  • scopus:84892502602
ISSN
1365-2796
DOI
10.1111/joim.12133
language
English
LU publication?
yes
id
0202decb-9cf0-4848-8051-49855578e4f8 (old id 4066208)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24010553?dopt=Abstract
date added to LUP
2013-10-01 11:11:38
date last changed
2017-11-19 03:04:44
@article{0202decb-9cf0-4848-8051-49855578e4f8,
  abstract     = {It is well established that subjects with moderately elevated plasma levels of C-reactive protein (CRP) have an increased risk of development of cardiovascular events. As atherosclerosis is a disease characterized by chronic arterial inflammation, it is possible that moderate increases in CRP level reflect the presence of plaque inflammation. To investigate this possibility we compared plasma levels of hsCRP the day before carotid endarterectomy with the degree of inflammation in the excised plaque tissue.},
  author       = {Grufman, Helena and Goncalves, Isabel and Edsfeldt, Andreas and Nitulescu, Mihaela and Persson, Ana and Nilsson, Marie MN and Nilsson, Jan},
  issn         = {1365-2796},
  language     = {eng},
  number       = {2},
  pages        = {127--133},
  publisher    = {Wiley-Blackwell Publishing Ltd},
  series       = {Journal of Internal Medicine},
  title        = {Plasma levels of high-sensitive C-reactive protein do not correlate with inflammatory activity in carotid atherosclerotic plaques.},
  url          = {http://dx.doi.org/10.1111/joim.12133},
  volume       = {275},
  year         = {2014},
}