Performance Evaluation of a Custom-Designed Contrast Media Injector in a 5-Tesla MRI Environment
(2025) In Bioengineering 12(6).- Abstract
The compatibility and safety of contrast media injectors (CMIs) at ultra-high magnetic field strengths remains a critical challenge. This study aimed to investigate a custom-designed CMI powered by a ceramic motor in a newly developed 5T MRI environment, comparing it with a commercial CMI commonly used in a clinic. Three key performance aspects of the CMI were assessed in the 5T environment: translational attraction force, injection flow rates, and total injected volume. Potential imaging artifacts were checked. The custom-designed CMI demonstrated robust performance in the 5T environment, maintaining injection accuracy across all test locations and ensuring translational attraction forces remained within safe thresholds, even in the... (More)
The compatibility and safety of contrast media injectors (CMIs) at ultra-high magnetic field strengths remains a critical challenge. This study aimed to investigate a custom-designed CMI powered by a ceramic motor in a newly developed 5T MRI environment, comparing it with a commercial CMI commonly used in a clinic. Three key performance aspects of the CMI were assessed in the 5T environment: translational attraction force, injection flow rates, and total injected volume. Potential imaging artifacts were checked. The custom-designed CMI demonstrated robust performance in the 5T environment, maintaining injection accuracy across all test locations and ensuring translational attraction forces remained within safe thresholds, even in the most challenging positions. Importantly, the custom-designed CMI exhibited no significant radiofrequency (RF) interference, and no imaging artifacts were observed across routine clinical sequences. In contrast, the commercial 3T CMI showed RF interference in several sensitive tests, such as the gradient echo (GRE) sequence with a 0° flip angle and frequency-based detection methods, underscoring the need for field-specific CMI designs tailored to ultra-high field environments. Further tests were performed in monkey livers and a human brain in vivo. The custom-designed CMI proved to be safe, accurate, and fully compatible with the 5T environment.
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- author
- Hu, Yuannan ; Sun, Wenbo ; Wang, Zhusha ; Wang, Wei ; Liao, Rufang ; Ruan, Zhao ; Li, Huan ; Xu, Haibo and Topgaard, Daniel LU
- organization
- publishing date
- 2025-06
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- 5T, contrast media injector, MRI, RF interference, ultra-high field
- in
- Bioengineering
- volume
- 12
- issue
- 6
- article number
- 566
- publisher
- MDPI AG
- external identifiers
-
- scopus:105009130574
- pmid:40564383
- ISSN
- 2306-5354
- DOI
- 10.3390/bioengineering12060566
- language
- English
- LU publication?
- yes
- additional info
- Publisher Copyright: © 2025 by the authors.
- id
- 411f388b-06d5-4c10-a2ce-e4c34caa8c09
- date added to LUP
- 2025-12-16 16:19:58
- date last changed
- 2025-12-17 03:00:09
@article{411f388b-06d5-4c10-a2ce-e4c34caa8c09,
abstract = {{<p>The compatibility and safety of contrast media injectors (CMIs) at ultra-high magnetic field strengths remains a critical challenge. This study aimed to investigate a custom-designed CMI powered by a ceramic motor in a newly developed 5T MRI environment, comparing it with a commercial CMI commonly used in a clinic. Three key performance aspects of the CMI were assessed in the 5T environment: translational attraction force, injection flow rates, and total injected volume. Potential imaging artifacts were checked. The custom-designed CMI demonstrated robust performance in the 5T environment, maintaining injection accuracy across all test locations and ensuring translational attraction forces remained within safe thresholds, even in the most challenging positions. Importantly, the custom-designed CMI exhibited no significant radiofrequency (RF) interference, and no imaging artifacts were observed across routine clinical sequences. In contrast, the commercial 3T CMI showed RF interference in several sensitive tests, such as the gradient echo (GRE) sequence with a 0° flip angle and frequency-based detection methods, underscoring the need for field-specific CMI designs tailored to ultra-high field environments. Further tests were performed in monkey livers and a human brain in vivo. The custom-designed CMI proved to be safe, accurate, and fully compatible with the 5T environment.</p>}},
author = {{Hu, Yuannan and Sun, Wenbo and Wang, Zhusha and Wang, Wei and Liao, Rufang and Ruan, Zhao and Li, Huan and Xu, Haibo and Topgaard, Daniel}},
issn = {{2306-5354}},
keywords = {{5T; contrast media injector; MRI; RF interference; ultra-high field}},
language = {{eng}},
number = {{6}},
publisher = {{MDPI AG}},
series = {{Bioengineering}},
title = {{Performance Evaluation of a Custom-Designed Contrast Media Injector in a 5-Tesla MRI Environment}},
url = {{http://dx.doi.org/10.3390/bioengineering12060566}},
doi = {{10.3390/bioengineering12060566}},
volume = {{12}},
year = {{2025}},
}