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Non-invasive gas monitoring in newborn infants using diode laser absorption spectroscopy: A case study

Lundin, Patrik LU ; Krite Svanberg, Emilie LU ; Cocola, Lorenzo LU ; Lewander, Märta LU ; Andersson-Engels, Stefan LU ; Jahr, John LU ; Fellman, Vineta LU ; Svanberg, Katarina LU and Svanberg, Sune LU (2012) Conference on Optical Diagnostics and Sensing XII - Toward Point-of-Care Diagnostics/4th Meeting of the Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissues In SPIE Conference Proceedings 8229.
Abstract
Non-invasive diode laser spectroscopy was, for the first time, used to assess gas content in the intestines and the lungs of a new-born, 4 kg, baby. Two gases, water vapor and oxygen, were studied with two low-power tunable diode lasers, illuminating the surface skin tissue and detecting the diffusely emerging light a few centimeters away. The light, having penetrated into the tissue, had experienced absorption by gas located in the lungs and in the intestines. Very distinct water vapor signals were obtained from the intestines while imprint from oxygen was lacking, as expected. Detectable, but minor, signals of water vapor were also obtained from the lungs, illuminating the armpit area and detecting below the collar bone. Water vapor... (More)
Non-invasive diode laser spectroscopy was, for the first time, used to assess gas content in the intestines and the lungs of a new-born, 4 kg, baby. Two gases, water vapor and oxygen, were studied with two low-power tunable diode lasers, illuminating the surface skin tissue and detecting the diffusely emerging light a few centimeters away. The light, having penetrated into the tissue, had experienced absorption by gas located in the lungs and in the intestines. Very distinct water vapor signals were obtained from the intestines while imprint from oxygen was lacking, as expected. Detectable, but minor, signals of water vapor were also obtained from the lungs, illuminating the armpit area and detecting below the collar bone. Water vapor signals were seen but again oxygen signals were lacking, now due to the difficulties of penetration of the oxygen probing light into the lungs of this full-term baby. Ultra-sound images were obtained both from the lungs and from the stomach of the baby. Based on dimensions and our experimental findings, we conclude, that for early pre-term babies, also oxygen should be detectable in the lungs, in addition to intestine and lung detection of water vapor. The present paper focuses on the studies of the intestines while the lung studies will be covered in a forthcoming paper. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
surfactant, gastrointestinal tract, NEC, colic, lungs, oxygen, water vapor, spectroscopy, Diode laser
in
SPIE Conference Proceedings
volume
8229
publisher
SPIE
conference name
Conference on Optical Diagnostics and Sensing XII - Toward Point-of-Care Diagnostics/4th Meeting of the Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissues
external identifiers
  • wos:000325299500003
  • wos:000301419300003
  • scopus:84858264239
ISSN
1996-756X
0277-786X
DOI
10.1117/12.907464
language
English
LU publication?
yes
id
add16091-789c-4b6b-a38b-e356232b871b (old id 4171668)
date added to LUP
2012-05-15 08:37:59
date last changed
2017-11-20 15:05:48
@inproceedings{add16091-789c-4b6b-a38b-e356232b871b,
  abstract     = {Non-invasive diode laser spectroscopy was, for the first time, used to assess gas content in the intestines and the lungs of a new-born, 4 kg, baby. Two gases, water vapor and oxygen, were studied with two low-power tunable diode lasers, illuminating the surface skin tissue and detecting the diffusely emerging light a few centimeters away. The light, having penetrated into the tissue, had experienced absorption by gas located in the lungs and in the intestines. Very distinct water vapor signals were obtained from the intestines while imprint from oxygen was lacking, as expected. Detectable, but minor, signals of water vapor were also obtained from the lungs, illuminating the armpit area and detecting below the collar bone. Water vapor signals were seen but again oxygen signals were lacking, now due to the difficulties of penetration of the oxygen probing light into the lungs of this full-term baby. Ultra-sound images were obtained both from the lungs and from the stomach of the baby. Based on dimensions and our experimental findings, we conclude, that for early pre-term babies, also oxygen should be detectable in the lungs, in addition to intestine and lung detection of water vapor. The present paper focuses on the studies of the intestines while the lung studies will be covered in a forthcoming paper.},
  author       = {Lundin, Patrik and Krite Svanberg, Emilie and Cocola, Lorenzo and Lewander, Märta and Andersson-Engels, Stefan and Jahr, John and Fellman, Vineta and Svanberg, Katarina and Svanberg, Sune},
  booktitle    = {SPIE Conference Proceedings},
  issn         = {1996-756X},
  keyword      = {surfactant,gastrointestinal tract,NEC,colic,lungs,oxygen,water vapor,spectroscopy,Diode laser},
  language     = {eng},
  publisher    = {SPIE},
  title        = {Non-invasive gas monitoring in newborn infants using diode laser absorption spectroscopy: A case study},
  url          = {http://dx.doi.org/10.1117/12.907464},
  volume       = {8229},
  year         = {2012},
}