Neuropsychological functions predict 1-and 3-year outcome in first-episode psychosis
(2006) In Acta Psychiatrica Scandinavica 113(2). p.102-111- Abstract
- Objective: To examine neuropsychological performance as a possible predictor of course and outcome in first-episode psychotic (FEP) patients. Method: A group of consecutive FEP patients (n = 120) tested with Wechsler Adult Intelligence Scales-Revised (WAIS-R) at baseline was compared with a healthy group (n = 30) matched for age, education and gender. Relationship between WAIS-R and both Brief Psychiatric Rating Scale and Global Assessment of Function (GAF) ratings were studied at baseline and at 1- and 3-year follow-ups. Results: The performance of FEP patients was significantly lower (P < 0.001) than that of healthy comparison subjects on all WAIS-R subtests except for Information and Comprehension. The WAIS-R scores of patients with... (More)
- Objective: To examine neuropsychological performance as a possible predictor of course and outcome in first-episode psychotic (FEP) patients. Method: A group of consecutive FEP patients (n = 120) tested with Wechsler Adult Intelligence Scales-Revised (WAIS-R) at baseline was compared with a healthy group (n = 30) matched for age, education and gender. Relationship between WAIS-R and both Brief Psychiatric Rating Scale and Global Assessment of Function (GAF) ratings were studied at baseline and at 1- and 3-year follow-ups. Results: The performance of FEP patients was significantly lower (P < 0.001) than that of healthy comparison subjects on all WAIS-R subtests except for Information and Comprehension. The WAIS-R scores of patients with schizophrenia syndromes (DSM-IV) were lower than those of patients with non-schizophrenia syndromes on Block Design. Low WAIS-R Full-Scale IQ scores in FEP patients predicted the presence of negative symptoms at 1-year follow-up and of low GAF ratings at 3-year follow-up. Conclusion: Neurocognitive performance at admission appears to predict various aspects of functional outcome in FEP. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/420017
- author
- Carlsson, Rickard LU ; Nyman, H ; Ganse, G and Cullberg, J
- organization
- publishing date
- 2006
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- outcome, first-episode, cognitive functions, neuropsychology, episode psychosis, schizophrenia
- in
- Acta Psychiatrica Scandinavica
- volume
- 113
- issue
- 2
- pages
- 102 - 111
- publisher
- Wiley-Blackwell
- external identifiers
-
- wos:000234662900005
- pmid:16423161
- scopus:33644758588
- pmid:16423161
- ISSN
- 1600-0447
- DOI
- 10.1111/j.1600-0447.2005.00661.x
- language
- English
- LU publication?
- yes
- id
- c5a49942-882d-4468-8708-7407c684958b (old id 420017)
- date added to LUP
- 2016-04-01 17:08:17
- date last changed
- 2022-01-29 00:39:11
@article{c5a49942-882d-4468-8708-7407c684958b, abstract = {{Objective: To examine neuropsychological performance as a possible predictor of course and outcome in first-episode psychotic (FEP) patients. Method: A group of consecutive FEP patients (n = 120) tested with Wechsler Adult Intelligence Scales-Revised (WAIS-R) at baseline was compared with a healthy group (n = 30) matched for age, education and gender. Relationship between WAIS-R and both Brief Psychiatric Rating Scale and Global Assessment of Function (GAF) ratings were studied at baseline and at 1- and 3-year follow-ups. Results: The performance of FEP patients was significantly lower (P < 0.001) than that of healthy comparison subjects on all WAIS-R subtests except for Information and Comprehension. The WAIS-R scores of patients with schizophrenia syndromes (DSM-IV) were lower than those of patients with non-schizophrenia syndromes on Block Design. Low WAIS-R Full-Scale IQ scores in FEP patients predicted the presence of negative symptoms at 1-year follow-up and of low GAF ratings at 3-year follow-up. Conclusion: Neurocognitive performance at admission appears to predict various aspects of functional outcome in FEP.}}, author = {{Carlsson, Rickard and Nyman, H and Ganse, G and Cullberg, J}}, issn = {{1600-0447}}, keywords = {{outcome; first-episode; cognitive functions; neuropsychology; episode psychosis; schizophrenia}}, language = {{eng}}, number = {{2}}, pages = {{102--111}}, publisher = {{Wiley-Blackwell}}, series = {{Acta Psychiatrica Scandinavica}}, title = {{Neuropsychological functions predict 1-and 3-year outcome in first-episode psychosis}}, url = {{http://dx.doi.org/10.1111/j.1600-0447.2005.00661.x}}, doi = {{10.1111/j.1600-0447.2005.00661.x}}, volume = {{113}}, year = {{2006}}, }