Contact dermatitis in children caused by diabetes devices
(2022) In Contact Dermatitis 87(5). p.406-413- Abstract
Background: Insulin pumps and glucose monitoring devices improve diabetes mellitus control and enhance patients' quality of life. However, a growing number of adverse cutaneous reactions related to the use of these devices have been reported. Objective: To investigate the culprits of localized contact dermatitis in paediatric patients with diabetes caused by insulin pumps and glucose monitoring devices. Methods: Retrospective analysis of 15 paediatric patients patch tested as part of a clinical investigation for skin reactions associated with insulin pumps and glucose monitoring devices. Results: Seven patients had positive patch test reactions to isobornyl acrylate (IBOA) and five had positive reactions to benzoyl peroxide (BP).... (More)
Background: Insulin pumps and glucose monitoring devices improve diabetes mellitus control and enhance patients' quality of life. However, a growing number of adverse cutaneous reactions related to the use of these devices have been reported. Objective: To investigate the culprits of localized contact dermatitis in paediatric patients with diabetes caused by insulin pumps and glucose monitoring devices. Methods: Retrospective analysis of 15 paediatric patients patch tested as part of a clinical investigation for skin reactions associated with insulin pumps and glucose monitoring devices. Results: Seven patients had positive patch test reactions to isobornyl acrylate (IBOA) and five had positive reactions to benzoyl peroxide (BP). Positive patch test reactions to materials from the glucose sensor and/or insulin pump were seen in 10 of the 15 patients. Three had positive reactions to adhesive remover wipe from Smith and Nephew Remove and four had reactions to EMLA plaster. Conclusion: A high share of patients showed positive reactions to IBOA and/or their medical devices (insulin pumps or glucose devices). A third of patients showed positive reactions to BP. The presence of additional unidentified allergens cannot be excluded, highlighting the importance of access to a full description of the chemical composition of the devices.
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- author
- Alves da Silva, Catarina ; Bregnhøj, Anne ; Mowitz, Martin LU ; Bruze, Magnus LU ; Andersen, Klaus Ejner and Sommerlund, Mette
- organization
- publishing date
- 2022
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- allergic contact dermatitis, benzoyl peroxide, children, diabetes mellitus, gas chromatography–mass spectrometry, glucose sensors, insulin infusion sets, irritant contact dermatitis, isobornyl acrylate, sesquiterpene lactone mix
- in
- Contact Dermatitis
- volume
- 87
- issue
- 5
- pages
- 406 - 413
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:35634681
- scopus:85131739831
- ISSN
- 0105-1873
- DOI
- 10.1111/cod.14166
- language
- English
- LU publication?
- yes
- id
- 42d7de3f-b8f2-4b8f-9c59-1a8e9beee3f1
- date added to LUP
- 2022-09-21 15:12:15
- date last changed
- 2024-09-20 04:42:31
@article{42d7de3f-b8f2-4b8f-9c59-1a8e9beee3f1, abstract = {{<p>Background: Insulin pumps and glucose monitoring devices improve diabetes mellitus control and enhance patients' quality of life. However, a growing number of adverse cutaneous reactions related to the use of these devices have been reported. Objective: To investigate the culprits of localized contact dermatitis in paediatric patients with diabetes caused by insulin pumps and glucose monitoring devices. Methods: Retrospective analysis of 15 paediatric patients patch tested as part of a clinical investigation for skin reactions associated with insulin pumps and glucose monitoring devices. Results: Seven patients had positive patch test reactions to isobornyl acrylate (IBOA) and five had positive reactions to benzoyl peroxide (BP). Positive patch test reactions to materials from the glucose sensor and/or insulin pump were seen in 10 of the 15 patients. Three had positive reactions to adhesive remover wipe from Smith and Nephew Remove and four had reactions to EMLA plaster. Conclusion: A high share of patients showed positive reactions to IBOA and/or their medical devices (insulin pumps or glucose devices). A third of patients showed positive reactions to BP. The presence of additional unidentified allergens cannot be excluded, highlighting the importance of access to a full description of the chemical composition of the devices.</p>}}, author = {{Alves da Silva, Catarina and Bregnhøj, Anne and Mowitz, Martin and Bruze, Magnus and Andersen, Klaus Ejner and Sommerlund, Mette}}, issn = {{0105-1873}}, keywords = {{allergic contact dermatitis; benzoyl peroxide; children; diabetes mellitus; gas chromatography–mass spectrometry; glucose sensors; insulin infusion sets; irritant contact dermatitis; isobornyl acrylate; sesquiterpene lactone mix}}, language = {{eng}}, number = {{5}}, pages = {{406--413}}, publisher = {{Wiley-Blackwell}}, series = {{Contact Dermatitis}}, title = {{Contact dermatitis in children caused by diabetes devices}}, url = {{http://dx.doi.org/10.1111/cod.14166}}, doi = {{10.1111/cod.14166}}, volume = {{87}}, year = {{2022}}, }