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Epidemiology of fractures in Iceland and secular trends in major osteoporotic fractures 1989-2008

Siggeirsdottir, K. ; Aspelund, T. ; Jonsson, Brynjolfur LU ; Mogensen, B. ; Gudmundsson, E. F. ; Gudnason, V. and Sigurdsson, G. (2014) In Osteoporosis International 25(1). p.211-219
Abstract
The incidence of the most common fracture types in Iceland is reported based on individual data from the Reykjavik Study 1967-2008. Time trend is reported for the major osteoporotic fractures (MOS) 1989-2008. This study aims to assess the incidence of all fractures in Iceland, with emphasis on the rate of hip fractures, and compare the incidence with other populations as well as examine the secular changes. Individuals from the prospective population-based cohort Reykjavik Study were examined between 1967 and 2008 (follow-up 26.5 years), which consisted of 9,116 men and 9,756 women born in 1907-1935, with age range 31-81 years. First fracture incidence was estimated using life table methods with age as the timescale. Fracture rate... (More)
The incidence of the most common fracture types in Iceland is reported based on individual data from the Reykjavik Study 1967-2008. Time trend is reported for the major osteoporotic fractures (MOS) 1989-2008. This study aims to assess the incidence of all fractures in Iceland, with emphasis on the rate of hip fractures, and compare the incidence with other populations as well as examine the secular changes. Individuals from the prospective population-based cohort Reykjavik Study were examined between 1967 and 2008 (follow-up 26.5 years), which consisted of 9,116 men and 9,756 women born in 1907-1935, with age range 31-81 years. First fracture incidence was estimated using life table methods with age as the timescale. Fracture rate increased proportionally with age between the sexes for vertebral and proximal humerus but disproportionally for hip and distal forearm fractures. The ratio of first fracture incidence between the sexes varied considerably by site: 2.65 for hip fractures and the highest for distal forearm fractures at 4.83. By the age of 75, 36.7 % of women and 21 % of men had sustained a fracture, taking into account competing risk of death. The incidence of hip fractures was similar to results previously published from USA, Sweden, Norway, and Scotland. The incidence of MOS fractures in both sexes decreased over the last decade, except hip fractures in men, which remained unchanged, as reflected in the women/men ratio for the hip, which changed from 2.6 to 1.7. This study adds information to scarce knowledge on the relative fracture incidence of different fractures. The incidence of MOS fractures increased in the latter part of the last century in both sexes and declined during the last decade, less dramatically for men. This information is important for planning health resources. (Less)
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author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Epidemiology, Fracture incidence, Major osteoporotic fractures, Secular, changes, The Reykjavik Study
in
Osteoporosis International
volume
25
issue
1
pages
211 - 219
publisher
Springer
external identifiers
  • wos:000329106000020
  • scopus:84891852604
  • pmid:23818208
ISSN
1433-2965
DOI
10.1007/s00198-013-2422-6
language
English
LU publication?
yes
id
4a734788-8c4a-43ef-956f-7cc7a1075720 (old id 4327114)
date added to LUP
2016-04-01 14:14:24
date last changed
2022-04-14 08:42:20
@article{4a734788-8c4a-43ef-956f-7cc7a1075720,
  abstract     = {{The incidence of the most common fracture types in Iceland is reported based on individual data from the Reykjavik Study 1967-2008. Time trend is reported for the major osteoporotic fractures (MOS) 1989-2008. This study aims to assess the incidence of all fractures in Iceland, with emphasis on the rate of hip fractures, and compare the incidence with other populations as well as examine the secular changes. Individuals from the prospective population-based cohort Reykjavik Study were examined between 1967 and 2008 (follow-up 26.5 years), which consisted of 9,116 men and 9,756 women born in 1907-1935, with age range 31-81 years. First fracture incidence was estimated using life table methods with age as the timescale. Fracture rate increased proportionally with age between the sexes for vertebral and proximal humerus but disproportionally for hip and distal forearm fractures. The ratio of first fracture incidence between the sexes varied considerably by site: 2.65 for hip fractures and the highest for distal forearm fractures at 4.83. By the age of 75, 36.7 % of women and 21 % of men had sustained a fracture, taking into account competing risk of death. The incidence of hip fractures was similar to results previously published from USA, Sweden, Norway, and Scotland. The incidence of MOS fractures in both sexes decreased over the last decade, except hip fractures in men, which remained unchanged, as reflected in the women/men ratio for the hip, which changed from 2.6 to 1.7. This study adds information to scarce knowledge on the relative fracture incidence of different fractures. The incidence of MOS fractures increased in the latter part of the last century in both sexes and declined during the last decade, less dramatically for men. This information is important for planning health resources.}},
  author       = {{Siggeirsdottir, K. and Aspelund, T. and Jonsson, Brynjolfur and Mogensen, B. and Gudmundsson, E. F. and Gudnason, V. and Sigurdsson, G.}},
  issn         = {{1433-2965}},
  keywords     = {{Epidemiology; Fracture incidence; Major osteoporotic fractures; Secular; changes; The Reykjavik Study}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{211--219}},
  publisher    = {{Springer}},
  series       = {{Osteoporosis International}},
  title        = {{Epidemiology of fractures in Iceland and secular trends in major osteoporotic fractures 1989-2008}},
  url          = {{http://dx.doi.org/10.1007/s00198-013-2422-6}},
  doi          = {{10.1007/s00198-013-2422-6}},
  volume       = {{25}},
  year         = {{2014}},
}