J-curve association between alcohol intake and varicose veins in Japan : The Shimane CoHRE Study
(2019) In Journal of Dermatology 46(10). p.902-906- Abstract
The effect of alcohol intake on varicose veins (VV) has not been determined by its consumption level. The aim of this study was to investigate the association between alcohol intake and VV in an elderly general population. Using a cross-sectional approach, the Shimane CoHRE Study data, comprising a total of 1060 participants, were analyzed. By multivariate regression analysis adjusted with basic characteristics, past work history, lifestyle-related factors and medical history, compared with non-drinkers, mild drinkers (<20.0 g/day) showed a significantly lower adjusted odds ratio (aOR) of VV (aOR = 0.64, P = 0.036). In a similar way, regular drinkers (1-5 days/week) showed a significantly lower aOR of VV when compared with occasional... (More)
The effect of alcohol intake on varicose veins (VV) has not been determined by its consumption level. The aim of this study was to investigate the association between alcohol intake and VV in an elderly general population. Using a cross-sectional approach, the Shimane CoHRE Study data, comprising a total of 1060 participants, were analyzed. By multivariate regression analysis adjusted with basic characteristics, past work history, lifestyle-related factors and medical history, compared with non-drinkers, mild drinkers (<20.0 g/day) showed a significantly lower adjusted odds ratio (aOR) of VV (aOR = 0.64, P = 0.036). In a similar way, regular drinkers (1-5 days/week) showed a significantly lower aOR of VV when compared with occasional drinkers (aOR = 0.57, P = 0.032). VV and alcohol intake showed J-curve relationships. In a stratified analysis by alcohol consumption levels, the association of smoking and VV were also observed in moderate to heavy drinkers and habitual drinkers. These findings can provide better understanding of pathophysiological mechanism and be used for evidence-based patient education.
(Less)
- author
- organization
- publishing date
- 2019-07-29
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Dermatology
- volume
- 46
- issue
- 10
- pages
- 902 - 906
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:85070475442
- pmid:31353631
- ISSN
- 1346-8138
- DOI
- 10.1111/1346-8138.15022
- language
- English
- LU publication?
- yes
- additional info
- © 2019 Japanese Dermatological Association.
- id
- 436ffc2b-ca40-40e6-b848-b07d1bcbec8d
- date added to LUP
- 2019-08-01 13:53:31
- date last changed
- 2024-09-18 07:39:46
@article{436ffc2b-ca40-40e6-b848-b07d1bcbec8d, abstract = {{<p>The effect of alcohol intake on varicose veins (VV) has not been determined by its consumption level. The aim of this study was to investigate the association between alcohol intake and VV in an elderly general population. Using a cross-sectional approach, the Shimane CoHRE Study data, comprising a total of 1060 participants, were analyzed. By multivariate regression analysis adjusted with basic characteristics, past work history, lifestyle-related factors and medical history, compared with non-drinkers, mild drinkers (<20.0 g/day) showed a significantly lower adjusted odds ratio (aOR) of VV (aOR = 0.64, P = 0.036). In a similar way, regular drinkers (1-5 days/week) showed a significantly lower aOR of VV when compared with occasional drinkers (aOR = 0.57, P = 0.032). VV and alcohol intake showed J-curve relationships. In a stratified analysis by alcohol consumption levels, the association of smoking and VV were also observed in moderate to heavy drinkers and habitual drinkers. These findings can provide better understanding of pathophysiological mechanism and be used for evidence-based patient education.</p>}}, author = {{Kohno, Kunie and Niihara, Hiroyuki and Hamano, Tsuyoshi and Takeda, Miwako and Nakagawa, Yusei and Shiwaku, Kuninori and Nabika, Toru and Zöller, Bengt and Li, Xinjun and Sundquist, Kristina and Sundquist, Jan and Morita, Eishin}}, issn = {{1346-8138}}, language = {{eng}}, month = {{07}}, number = {{10}}, pages = {{902--906}}, publisher = {{Wiley-Blackwell}}, series = {{Journal of Dermatology}}, title = {{J-curve association between alcohol intake and varicose veins in Japan : The Shimane CoHRE Study}}, url = {{http://dx.doi.org/10.1111/1346-8138.15022}}, doi = {{10.1111/1346-8138.15022}}, volume = {{46}}, year = {{2019}}, }