Low myelinated nerve-fibre density may lead to symptoms associated with nerve entrapment in vibration-induced neuropathy.
Dahlin, Lars LU
; Sandén, Helena
; Dahlin, Erik
; Zimmerman, Malin
LU
; Thomsen, Niels
LU
and Björkman, Anders
LU
(2014)
In Journal of Occupational Medicine and Toxicology
9(1).
- Abstract
- Prolonged exposure to hand-held vibrating tools may cause a hand-arm vibration syndrome (HAVS), sometimes with individual susceptibility. The neurological symptoms seen in HAVS are similar to symptoms seen in patients with carpal tunnel syndrome (CTS) and there is a strong relationship between CTS and the use of vibrating tools. Vibration exposure to the hand is known to induce demyelination of nerve fibres and to reduce the density of myelinated nerve fibres in the nerve trunks. In view of current knowledge regarding the clinical effects of low nerve-fibre density in patients with neuropathies of varying aetiologies, such as diabetes, and that such a low density may lead to nerve entrapment symptoms, a reduction in myelinated nerve fibres... (More)
- Prolonged exposure to hand-held vibrating tools may cause a hand-arm vibration syndrome (HAVS), sometimes with individual susceptibility. The neurological symptoms seen in HAVS are similar to symptoms seen in patients with carpal tunnel syndrome (CTS) and there is a strong relationship between CTS and the use of vibrating tools. Vibration exposure to the hand is known to induce demyelination of nerve fibres and to reduce the density of myelinated nerve fibres in the nerve trunks. In view of current knowledge regarding the clinical effects of low nerve-fibre density in patients with neuropathies of varying aetiologies, such as diabetes, and that such a low density may lead to nerve entrapment symptoms, a reduction in myelinated nerve fibres may be a key factor behind the symptoms also seen in patients with HAVS and CTS. Furthermore, a reduced nerve-fibre density may result in a changed afferent signal pattern, resulting in turn in alterations in the brain, further prompting the symptoms seen in patients with HAVS and CTS. We conclude that a low nerve-fibre density lead to symptoms associated with nerve entrapment, such as CTS, in some patients with HAVS. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4383712
- author
- Dahlin, Lars
LU
; Sandén, Helena
; Dahlin, Erik
; Zimmerman, Malin
LU
; Thomsen, Niels
LU
and Björkman, Anders
LU
- organization
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Occupational Medicine and Toxicology
- volume
- 9
- issue
- 1
- article number
- 7
- publisher
- BioMed Central (BMC)
- external identifiers
-
- pmid:24606755
- wos:000333364700001
- scopus:84898004046
- pmid:24606755
- ISSN
- 1745-6673
- DOI
- 10.1186/1745-6673-9-7
- language
- English
- LU publication?
- yes
- id
- a2eb5110-e488-4668-a51a-e5de82ad55dd (old id 4383712)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/24606755?dopt=Abstract
- date added to LUP
- 2016-04-01 14:25:35
- date last changed
- 2022-04-06 18:28:43
@article{a2eb5110-e488-4668-a51a-e5de82ad55dd,
abstract = {{Prolonged exposure to hand-held vibrating tools may cause a hand-arm vibration syndrome (HAVS), sometimes with individual susceptibility. The neurological symptoms seen in HAVS are similar to symptoms seen in patients with carpal tunnel syndrome (CTS) and there is a strong relationship between CTS and the use of vibrating tools. Vibration exposure to the hand is known to induce demyelination of nerve fibres and to reduce the density of myelinated nerve fibres in the nerve trunks. In view of current knowledge regarding the clinical effects of low nerve-fibre density in patients with neuropathies of varying aetiologies, such as diabetes, and that such a low density may lead to nerve entrapment symptoms, a reduction in myelinated nerve fibres may be a key factor behind the symptoms also seen in patients with HAVS and CTS. Furthermore, a reduced nerve-fibre density may result in a changed afferent signal pattern, resulting in turn in alterations in the brain, further prompting the symptoms seen in patients with HAVS and CTS. We conclude that a low nerve-fibre density lead to symptoms associated with nerve entrapment, such as CTS, in some patients with HAVS.}},
author = {{Dahlin, Lars and Sandén, Helena and Dahlin, Erik and Zimmerman, Malin and Thomsen, Niels and Björkman, Anders}},
issn = {{1745-6673}},
language = {{eng}},
number = {{1}},
publisher = {{BioMed Central (BMC)}},
series = {{Journal of Occupational Medicine and Toxicology}},
title = {{Low myelinated nerve-fibre density may lead to symptoms associated with nerve entrapment in vibration-induced neuropathy.}},
url = {{https://lup.lub.lu.se/search/files/3970083/4645507}},
doi = {{10.1186/1745-6673-9-7}},
volume = {{9}},
year = {{2014}},
}