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Special considerations for the treatment of chronic kidney disease in the elderly

Corsonello, Andrea; Fusco, Sergio; Bustacchini, Silvia; Chiatti, Carlos LU ; Moresi, Raffaella; Bonfigli, Anna Rita; Di Stefano, Giuseppina and Lattanzio, Fabrizia (2016) In Expert Review of Clinical Pharmacology 9(5). p.727-737
Abstract

Chronic kidney disease (CKD) is common in older adults, and its burden is expected to increase in older populations. Even if the knowledge on the approach to older patient with CKD is still evolving, current guidelines for pharmacological management of CKD does not include specific recommendations for older patients. Additionally, decision-making on renal replacement therapy (RRT) for older patients is far from being evidence-based, and despite the improvement in dialysis outcomes, RRT may cause more harm than benefit compared with conservative care when prognostic stratification is not carefully assessed. The use of comprehensive geriatric assessment tools could help clinicians in applying a more informed decision-making. Finally,... (More)

Chronic kidney disease (CKD) is common in older adults, and its burden is expected to increase in older populations. Even if the knowledge on the approach to older patient with CKD is still evolving, current guidelines for pharmacological management of CKD does not include specific recommendations for older patients. Additionally, decision-making on renal replacement therapy (RRT) for older patients is far from being evidence-based, and despite the improvement in dialysis outcomes, RRT may cause more harm than benefit compared with conservative care when prognostic stratification is not carefully assessed. The use of comprehensive geriatric assessment tools could help clinicians in applying a more informed decision-making. Finally, physical exercise and rehabilitation interventions also represents a promising therapeutic strategy.

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Please use this url to cite or link to this publication:
author
publishing date
type
Contribution to journal
publication status
published
keywords
acidosis, albuminuria, anemia, Chronic kidney disease, comprehensive geriatric assessment, diabetes, hypertension, osteoporosis, rehabilitation, renal replacement therapy
in
Expert Review of Clinical Pharmacology
volume
9
issue
5
pages
11 pages
publisher
Taylor & Francis
external identifiers
  • scopus:84961213273
ISSN
1751-2433
DOI
10.1586/17512433.2016.1155448
language
English
LU publication?
no
id
43e55b53-41af-4e17-9536-755a31035ab9
date added to LUP
2017-03-16 11:41:10
date last changed
2017-07-23 05:26:16
@article{43e55b53-41af-4e17-9536-755a31035ab9,
  abstract     = {<p>Chronic kidney disease (CKD) is common in older adults, and its burden is expected to increase in older populations. Even if the knowledge on the approach to older patient with CKD is still evolving, current guidelines for pharmacological management of CKD does not include specific recommendations for older patients. Additionally, decision-making on renal replacement therapy (RRT) for older patients is far from being evidence-based, and despite the improvement in dialysis outcomes, RRT may cause more harm than benefit compared with conservative care when prognostic stratification is not carefully assessed. The use of comprehensive geriatric assessment tools could help clinicians in applying a more informed decision-making. Finally, physical exercise and rehabilitation interventions also represents a promising therapeutic strategy.</p>},
  author       = {Corsonello, Andrea and Fusco, Sergio and Bustacchini, Silvia and Chiatti, Carlos and Moresi, Raffaella and Bonfigli, Anna Rita and Di Stefano, Giuseppina and Lattanzio, Fabrizia},
  issn         = {1751-2433},
  keyword      = {acidosis,albuminuria,anemia,Chronic kidney disease,comprehensive geriatric assessment,diabetes,hypertension,osteoporosis,rehabilitation,renal replacement therapy},
  language     = {eng},
  month        = {05},
  number       = {5},
  pages        = {727--737},
  publisher    = {Taylor & Francis},
  series       = {Expert Review of Clinical Pharmacology},
  title        = {Special considerations for the treatment of chronic kidney disease in the elderly},
  url          = {http://dx.doi.org/10.1586/17512433.2016.1155448},
  volume       = {9},
  year         = {2016},
}