Special considerations for the treatment of chronic kidney disease in the elderly
(2016) In Expert Review of Clinical Pharmacology 9(5). p.727-737- Abstract
Chronic kidney disease (CKD) is common in older adults, and its burden is expected to increase in older populations. Even if the knowledge on the approach to older patient with CKD is still evolving, current guidelines for pharmacological management of CKD does not include specific recommendations for older patients. Additionally, decision-making on renal replacement therapy (RRT) for older patients is far from being evidence-based, and despite the improvement in dialysis outcomes, RRT may cause more harm than benefit compared with conservative care when prognostic stratification is not carefully assessed. The use of comprehensive geriatric assessment tools could help clinicians in applying a more informed decision-making. Finally,... (More)
Chronic kidney disease (CKD) is common in older adults, and its burden is expected to increase in older populations. Even if the knowledge on the approach to older patient with CKD is still evolving, current guidelines for pharmacological management of CKD does not include specific recommendations for older patients. Additionally, decision-making on renal replacement therapy (RRT) for older patients is far from being evidence-based, and despite the improvement in dialysis outcomes, RRT may cause more harm than benefit compared with conservative care when prognostic stratification is not carefully assessed. The use of comprehensive geriatric assessment tools could help clinicians in applying a more informed decision-making. Finally, physical exercise and rehabilitation interventions also represents a promising therapeutic strategy.
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- author
- Corsonello, Andrea ; Fusco, Sergio ; Bustacchini, Silvia ; Chiatti, Carlos LU ; Moresi, Raffaella ; Bonfigli, Anna Rita ; Di Stefano, Giuseppina and Lattanzio, Fabrizia
- publishing date
- 2016-05-03
- type
- Contribution to journal
- publication status
- published
- keywords
- acidosis, albuminuria, anemia, Chronic kidney disease, comprehensive geriatric assessment, diabetes, hypertension, osteoporosis, rehabilitation, renal replacement therapy
- in
- Expert Review of Clinical Pharmacology
- volume
- 9
- issue
- 5
- pages
- 11 pages
- publisher
- Taylor & Francis
- external identifiers
-
- scopus:84961213273
- pmid:26885869
- ISSN
- 1751-2433
- DOI
- 10.1586/17512433.2016.1155448
- language
- English
- LU publication?
- no
- id
- 43e55b53-41af-4e17-9536-755a31035ab9
- date added to LUP
- 2017-03-16 11:41:10
- date last changed
- 2025-01-07 09:50:27
@article{43e55b53-41af-4e17-9536-755a31035ab9,
abstract = {{<p>Chronic kidney disease (CKD) is common in older adults, and its burden is expected to increase in older populations. Even if the knowledge on the approach to older patient with CKD is still evolving, current guidelines for pharmacological management of CKD does not include specific recommendations for older patients. Additionally, decision-making on renal replacement therapy (RRT) for older patients is far from being evidence-based, and despite the improvement in dialysis outcomes, RRT may cause more harm than benefit compared with conservative care when prognostic stratification is not carefully assessed. The use of comprehensive geriatric assessment tools could help clinicians in applying a more informed decision-making. Finally, physical exercise and rehabilitation interventions also represents a promising therapeutic strategy.</p>}},
author = {{Corsonello, Andrea and Fusco, Sergio and Bustacchini, Silvia and Chiatti, Carlos and Moresi, Raffaella and Bonfigli, Anna Rita and Di Stefano, Giuseppina and Lattanzio, Fabrizia}},
issn = {{1751-2433}},
keywords = {{acidosis; albuminuria; anemia; Chronic kidney disease; comprehensive geriatric assessment; diabetes; hypertension; osteoporosis; rehabilitation; renal replacement therapy}},
language = {{eng}},
month = {{05}},
number = {{5}},
pages = {{727--737}},
publisher = {{Taylor & Francis}},
series = {{Expert Review of Clinical Pharmacology}},
title = {{Special considerations for the treatment of chronic kidney disease in the elderly}},
url = {{http://dx.doi.org/10.1586/17512433.2016.1155448}},
doi = {{10.1586/17512433.2016.1155448}},
volume = {{9}},
year = {{2016}},
}