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Controlled short-linkage assembly of functional nano-objects

Chaudhary, Shilpi LU ; Kamra, Tripta LU ; Uddin, Khan Mohammad Ahsan; Snezhkova, Olesia LU ; Jayawardena, H. Surangi N.; Yan, Mingdi; Montelius, Lars; Schnadt, Joachim LU and Ye, Lei LU (2014) In Applied Surface Science 300. p.22-28
Abstract
In this work, we report a method that allows the deterministic, photo-controlled covalent assembly of nanoparticles directly on surface. As a model system, we study the conjugation of molecularly imprinted polymer (MIP) nanoparticles on a glass surface and confirm that the immobilized nanoparticles maintain their molecular recognition functionality. The glass slide was first modified with perfluorophenylazide and then used to bind MIP nanoparticles under UV irradiation. After each step the surface was analyzed by water contact angle measurement, fluorescence microscopy, scanning electron microscopy, and/or synchrotron-based X-ray photoelectron spectroscopy. The MIP nanoparticles immobilized on the glass surface remained stable and... (More)
In this work, we report a method that allows the deterministic, photo-controlled covalent assembly of nanoparticles directly on surface. As a model system, we study the conjugation of molecularly imprinted polymer (MIP) nanoparticles on a glass surface and confirm that the immobilized nanoparticles maintain their molecular recognition functionality. The glass slide was first modified with perfluorophenylazide and then used to bind MIP nanoparticles under UV irradiation. After each step the surface was analyzed by water contact angle measurement, fluorescence microscopy, scanning electron microscopy, and/or synchrotron-based X-ray photoelectron spectroscopy. The MIP nanoparticles immobilized on the glass surface remained stable and maintained specific binding for the template molecule, propranolol. The method developed in this work allows MIP nanoparticles to be directly coupled to a flat surface, offering a straightforward means to construct robust chemical sensors. Using the reported photo conjugation method, it is possible to generate patterned assembly of nanoparticles using a photomask. Since perfluorophenylazide-based photochemistry works with all kinds of organic material, the method developed in this work is expected to enable immobilization of not only MIPs but also other kinds of organic and inorganic-organic core-shell particles for various applications involving photon or electron transfer. (C) 2014 The Authors. Published by Elsevier B.V. All rights reserved. (Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Molecular imprinting, Nanoparticles, Photocoupling, X-ray photoelectron, spectroscopy, Immobilization
in
Applied Surface Science
volume
300
pages
22 - 28
publisher
Elsevier
external identifiers
  • wos:000333105500004
  • scopus:84896493288
ISSN
1873-5584
DOI
10.1016/j.apsusc.2014.01.174
language
English
LU publication?
yes
id
44935977-a63b-4899-b226-5bbf5b6cc6e8 (old id 4407449)
date added to LUP
2014-04-28 14:48:43
date last changed
2017-01-01 03:17:27
@article{44935977-a63b-4899-b226-5bbf5b6cc6e8,
  abstract     = {In this work, we report a method that allows the deterministic, photo-controlled covalent assembly of nanoparticles directly on surface. As a model system, we study the conjugation of molecularly imprinted polymer (MIP) nanoparticles on a glass surface and confirm that the immobilized nanoparticles maintain their molecular recognition functionality. The glass slide was first modified with perfluorophenylazide and then used to bind MIP nanoparticles under UV irradiation. After each step the surface was analyzed by water contact angle measurement, fluorescence microscopy, scanning electron microscopy, and/or synchrotron-based X-ray photoelectron spectroscopy. The MIP nanoparticles immobilized on the glass surface remained stable and maintained specific binding for the template molecule, propranolol. The method developed in this work allows MIP nanoparticles to be directly coupled to a flat surface, offering a straightforward means to construct robust chemical sensors. Using the reported photo conjugation method, it is possible to generate patterned assembly of nanoparticles using a photomask. Since perfluorophenylazide-based photochemistry works with all kinds of organic material, the method developed in this work is expected to enable immobilization of not only MIPs but also other kinds of organic and inorganic-organic core-shell particles for various applications involving photon or electron transfer. (C) 2014 The Authors. Published by Elsevier B.V. All rights reserved.},
  author       = {Chaudhary, Shilpi and Kamra, Tripta and Uddin, Khan Mohammad Ahsan and Snezhkova, Olesia and Jayawardena, H. Surangi N. and Yan, Mingdi and Montelius, Lars and Schnadt, Joachim and Ye, Lei},
  issn         = {1873-5584},
  keyword      = {Molecular imprinting,Nanoparticles,Photocoupling,X-ray photoelectron,spectroscopy,Immobilization},
  language     = {eng},
  pages        = {22--28},
  publisher    = {Elsevier},
  series       = {Applied Surface Science},
  title        = {Controlled short-linkage assembly of functional nano-objects},
  url          = {http://dx.doi.org/10.1016/j.apsusc.2014.01.174},
  volume       = {300},
  year         = {2014},
}