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Two new biologically active cyclopentenones from Dasyseyphus sp A47-98

Mierau, V ; Sterner, Olov LU and Anke, T (2004) In Journal of Antibiotics 57(5). p.311-315
Abstract
Two new biological active cyclopentenones VM 4798-1a (1a) and VM 4798-1b (1b) were obtained as a 3 : 1 inseparable mixture from fermentations of Dasyscyphus sp. A47-98. The mixture of the two isomers showed cytotoxic and weak antibacterial and antifungal properties. VM 4898-1 (2-hydroxy-3,4-dimethyl-2-cyclopenten-1-one, 4), produced by another Dasyscyphus sp. showed no significant biological activity. The structures were elucidated by NMR techniques.
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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Antibiotics
volume
57
issue
5
pages
311 - 315
publisher
Japan Antibiotics Research Association
external identifiers
  • wos:000221708600001
  • pmid:15303491
  • scopus:3042561906
ISSN
0021-8820
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Organic chemistry (S/LTH) (011001240)
id
4408e954-b42a-4892-bc0f-6f360a2c4cb1 (old id 141224)
alternative location
http://www.antibiotics.or.jp/journal/contents/vol-57/full_text/57-5/ja57_0311.pdf
http://www.antibiotics.or.jp/journal/contents/vol-57/57-5_contents.htm
date added to LUP
2016-04-01 17:06:33
date last changed
2022-01-29 00:23:04
@article{4408e954-b42a-4892-bc0f-6f360a2c4cb1,
  abstract     = {{Two new biological active cyclopentenones VM 4798-1a (1a) and VM 4798-1b (1b) were obtained as a 3 : 1 inseparable mixture from fermentations of Dasyscyphus sp. A47-98. The mixture of the two isomers showed cytotoxic and weak antibacterial and antifungal properties. VM 4898-1 (2-hydroxy-3,4-dimethyl-2-cyclopenten-1-one, 4), produced by another Dasyscyphus sp. showed no significant biological activity. The structures were elucidated by NMR techniques.}},
  author       = {{Mierau, V and Sterner, Olov and Anke, T}},
  issn         = {{0021-8820}},
  language     = {{eng}},
  number       = {{5}},
  pages        = {{311--315}},
  publisher    = {{Japan Antibiotics Research Association}},
  series       = {{Journal of Antibiotics}},
  title        = {{Two new biologically active cyclopentenones from Dasyseyphus sp A47-98}},
  url          = {{http://www.antibiotics.or.jp/journal/contents/vol-57/full_text/57-5/ja57_0311.pdf}},
  volume       = {{57}},
  year         = {{2004}},
}