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Serological assessment for celiac disease in IgA deficient adults.

Wang, Ning; Truedsson, Lennart LU ; Elvin, Kerstin; Andersson, Bengt A; Rönnelid, Johan; Mincheva-Nilsson, Lucia; Lindkvist, Annica; Ludvigsson, Jonas F; Hammarström, Lennart and Dahle, Charlotte (2014) In PLoS ONE 9(4).
Abstract
Selective immunoglobulin A deficiency is the most common primary immunodeficiency disorder that is strongly overrepresented among patients with celiac disease (CD). IgG antibodies against tissue transglutaminase (tTG) and deamidated gliadin peptides (DGP) serve as serological markers for CD in IgA deficient individuals, although the diagnostic value remains uncertain. The aim of this study was to investigate the prevalence of these markers in a large cohort of IgA deficient adults with confirmed or suspected CD and relate the findings to gluten free diet.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
PLoS ONE
volume
9
issue
4
publisher
Public Library of Science
external identifiers
  • pmid:24709954
  • wos:000334159800025
  • scopus:84899438820
ISSN
1932-6203
DOI
10.1371/journal.pone.0093180
language
English
LU publication?
yes
id
4698be70-fd3c-4ea3-9319-95adcc8ad218 (old id 4430685)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24709954?dopt=Abstract
date added to LUP
2014-05-06 19:29:33
date last changed
2017-10-22 04:29:01
@article{4698be70-fd3c-4ea3-9319-95adcc8ad218,
  abstract     = {Selective immunoglobulin A deficiency is the most common primary immunodeficiency disorder that is strongly overrepresented among patients with celiac disease (CD). IgG antibodies against tissue transglutaminase (tTG) and deamidated gliadin peptides (DGP) serve as serological markers for CD in IgA deficient individuals, although the diagnostic value remains uncertain. The aim of this study was to investigate the prevalence of these markers in a large cohort of IgA deficient adults with confirmed or suspected CD and relate the findings to gluten free diet.},
  articleno    = {e93180},
  author       = {Wang, Ning and Truedsson, Lennart and Elvin, Kerstin and Andersson, Bengt A and Rönnelid, Johan and Mincheva-Nilsson, Lucia and Lindkvist, Annica and Ludvigsson, Jonas F and Hammarström, Lennart and Dahle, Charlotte},
  issn         = {1932-6203},
  language     = {eng},
  number       = {4},
  publisher    = {Public Library of Science},
  series       = {PLoS ONE},
  title        = {Serological assessment for celiac disease in IgA deficient adults.},
  url          = {http://dx.doi.org/10.1371/journal.pone.0093180},
  volume       = {9},
  year         = {2014},
}