Human endogenous peptide p33 inhibits detrimental effects of LL-37 on osteoblast viability.
Svensson, Daniel LU ; Westman, Johannes LU ; Wickström, Claes LU ; Jönsson, Daniel LU ; Herwald, Heiko LU
and Nilsson, Bengt-Olof
LU
(2015)
In Journal of Periodontal Research
50(1).
p.80-88
- Abstract
- High levels of the antimicrobial peptide, LL-37, are detected in gingival crevicular fluid from patients with chronic periodontitis. LL-37 not only shows antimicrobial activity but also affects host-cell viability. The objective of the present study was to identify endogenous mechanisms that antagonize the detrimental effects of LL-37 on osteoblast viability, focusing on the human peptide p33 expressed on the surface of various cell types.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4431137
- author
- Svensson, Daniel
LU
; Westman, Johannes
LU
; Wickström, Claes
LU
; Jönsson, Daniel
LU
; Herwald, Heiko
LU
and Nilsson, Bengt-Olof
LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Periodontal Research
- volume
- 50
- issue
- 1
- pages
- 80 - 88
- publisher
- Wiley-Blackwell
- external identifiers
-
- pmid:24697598
- wos:000347467600010
- scopus:84920800294
- pmid:24697598
- ISSN
- 1600-0765
- DOI
- 10.1111/jre.12184
- project
- Effects of the antimicrobial peptide LL-37 on host cell viability
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Vascular Physiology (013212034), Mucosal biology (013212033), Division of Infection Medicine (BMC) (013024020)
- id
- d4cbf236-5a7e-4b71-96c5-75f1e8980ae1 (old id 4431137)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/24697598?dopt=Abstract
- date added to LUP
- 2016-04-01 10:21:38
- date last changed
- 2022-04-27 21:18:31
@article{d4cbf236-5a7e-4b71-96c5-75f1e8980ae1,
abstract = {{High levels of the antimicrobial peptide, LL-37, are detected in gingival crevicular fluid from patients with chronic periodontitis. LL-37 not only shows antimicrobial activity but also affects host-cell viability. The objective of the present study was to identify endogenous mechanisms that antagonize the detrimental effects of LL-37 on osteoblast viability, focusing on the human peptide p33 expressed on the surface of various cell types.}},
author = {{Svensson, Daniel and Westman, Johannes and Wickström, Claes and Jönsson, Daniel and Herwald, Heiko and Nilsson, Bengt-Olof}},
issn = {{1600-0765}},
language = {{eng}},
number = {{1}},
pages = {{80--88}},
publisher = {{Wiley-Blackwell}},
series = {{Journal of Periodontal Research}},
title = {{Human endogenous peptide p33 inhibits detrimental effects of LL-37 on osteoblast viability.}},
url = {{http://dx.doi.org/10.1111/jre.12184}},
doi = {{10.1111/jre.12184}},
volume = {{50}},
year = {{2015}},
}