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Quantification of myocardial salvage by myocardial perfusion SPECT and cardiac magnetic resonance - reference standards for ECG development.

Engblom, Henrik LU ; Aletras, Anthony LU ; Heiberg, Einar LU ; Arheden, Håkan LU and Carlsson, Marcus LU (2014) In Journal of Electrocardiology 47(4). p.525-534
Abstract
In order to determine the cardioprotective efficacy of acute reperfusion therapy, assessed as myocardial salvage, in patients with acute coronary occlusion, the final myocardial infarct (MI) size needs to be related to the amount of ischemic myocardium during coronary occlusion, referred to as the myocardium at risk (MaR). There are currently several imaging approaches available for quantification of both MI size and MaR in vivo of which some have been validated both in pre-clinical and clinical settings. These methods often involve the use of either myocardial perfusion SPECT or cardiac magnetic resonance (CMR). These imaging methods could potentially be used to further develop and validate ECG methods for determination of MI size and... (More)
In order to determine the cardioprotective efficacy of acute reperfusion therapy, assessed as myocardial salvage, in patients with acute coronary occlusion, the final myocardial infarct (MI) size needs to be related to the amount of ischemic myocardium during coronary occlusion, referred to as the myocardium at risk (MaR). There are currently several imaging approaches available for quantification of both MI size and MaR in vivo of which some have been validated both in pre-clinical and clinical settings. These methods often involve the use of either myocardial perfusion SPECT or cardiac magnetic resonance (CMR). These imaging methods could potentially be used to further develop and validate ECG methods for determination of MI size and MaR. Therefore, the aim of the present review is to give an overview of myocardial perfusion SPECT and CMR methods available for assessment of myocardial salvage by determination of MI size and MaR. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Electrocardiology
volume
47
issue
4
pages
525 - 534
publisher
Elsevier
external identifiers
  • pmid:24866753
  • wos:000340511400019
  • scopus:84905101600
ISSN
1532-8430
DOI
10.1016/j.jelectrocard.2014.04.001
language
English
LU publication?
yes
id
c2a628e7-d31b-4cf6-a77a-5b429076eef7 (old id 4452454)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24866753?dopt=Abstract
date added to LUP
2014-06-06 21:18:38
date last changed
2017-01-01 03:24:06
@article{c2a628e7-d31b-4cf6-a77a-5b429076eef7,
  abstract     = {In order to determine the cardioprotective efficacy of acute reperfusion therapy, assessed as myocardial salvage, in patients with acute coronary occlusion, the final myocardial infarct (MI) size needs to be related to the amount of ischemic myocardium during coronary occlusion, referred to as the myocardium at risk (MaR). There are currently several imaging approaches available for quantification of both MI size and MaR in vivo of which some have been validated both in pre-clinical and clinical settings. These methods often involve the use of either myocardial perfusion SPECT or cardiac magnetic resonance (CMR). These imaging methods could potentially be used to further develop and validate ECG methods for determination of MI size and MaR. Therefore, the aim of the present review is to give an overview of myocardial perfusion SPECT and CMR methods available for assessment of myocardial salvage by determination of MI size and MaR.},
  author       = {Engblom, Henrik and Aletras, Anthony and Heiberg, Einar and Arheden, Håkan and Carlsson, Marcus},
  issn         = {1532-8430},
  language     = {eng},
  number       = {4},
  pages        = {525--534},
  publisher    = {Elsevier},
  series       = {Journal of Electrocardiology},
  title        = {Quantification of myocardial salvage by myocardial perfusion SPECT and cardiac magnetic resonance - reference standards for ECG development.},
  url          = {http://dx.doi.org/10.1016/j.jelectrocard.2014.04.001},
  volume       = {47},
  year         = {2014},
}