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Occupational noise exposure and risk of incident stroke : a pooled study of five Scandinavian cohorts

Thacher, Jesse D. LU ; Roswall, Nina ; Lissåker, Claudia ; Aasvang, Gunn Marit ; Albin, Maria LU ; Andersson, Eva M. ; Engström, Gunnar LU ; Eriksson, Charlotta ; Hvidtfeldt, Ulla Arthur and Ketzel, Matthias , et al. (2022) In Occupational and Environmental Medicine 79(9). p.594-601
Abstract

Objectives: To investigate the association between occupational noise exposure and stroke incidence in a pooled study of five Scandinavian cohorts (NordSOUND). Methods: We pooled and harmonised data from five Scandinavian cohorts resulting in 78 389 participants. We obtained job data from national registries or questionnaires and recoded these to match a job-exposure matrix developed in Sweden, which specified the annual average daily noise exposure in five exposure classes (LAeq8h): <70, 70-74, 75-79, 80-84, ≥85 dB(A). We identified residential address history and estimated 1-year average road traffic noise at baseline. Using national patient and mortality registers, we identified 7777 stroke cases with a median follow-up of 20.2... (More)

Objectives: To investigate the association between occupational noise exposure and stroke incidence in a pooled study of five Scandinavian cohorts (NordSOUND). Methods: We pooled and harmonised data from five Scandinavian cohorts resulting in 78 389 participants. We obtained job data from national registries or questionnaires and recoded these to match a job-exposure matrix developed in Sweden, which specified the annual average daily noise exposure in five exposure classes (LAeq8h): <70, 70-74, 75-79, 80-84, ≥85 dB(A). We identified residential address history and estimated 1-year average road traffic noise at baseline. Using national patient and mortality registers, we identified 7777 stroke cases with a median follow-up of 20.2 years. Analyses were conducted using Cox proportional hazards models adjusting for individual and area-level potential confounders. Results: Exposure to occupational noise at baseline was not associated with overall stroke in the fully adjusted models. For ischaemic stroke, occupational noise was associated with HRs (95% CI) of 1.08 (0.98 to 1.20), 1.09 (0.97 to 1.24) and 1.06 (0.92 to 1.21) in the 75-79, 80-84 and ≥85 dB(A) exposure groups, compared with <70 dB(A), respectively. In subanalyses using time-varying occupational noise exposure, we observed an indication of higher stroke risk among the most exposed (≥85 dB(A)), particularly when restricting analyses to people exposed to occupational noise within the last year (HR: 1.27; 95% CI: 0.99 to 1.63). Conclusions: We found no association between occupational noise and risk of overall stroke after adjustment for confounders. However, the non-significantly increased risk of ischaemic stroke warrants further investigation.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
epidemiology, noise, public health
in
Occupational and Environmental Medicine
volume
79
issue
9
pages
594 - 601
publisher
BMJ Publishing Group
external identifiers
  • pmid:35450950
  • scopus:85130847985
ISSN
1351-0711
DOI
10.1136/oemed-2021-108053
language
English
LU publication?
yes
additional info
Publisher Copyright: © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
id
44a661f5-2704-4075-8c44-50b6e9553c9b
date added to LUP
2022-08-19 09:38:18
date last changed
2024-03-21 05:05:03
@article{44a661f5-2704-4075-8c44-50b6e9553c9b,
  abstract     = {{<p>Objectives: To investigate the association between occupational noise exposure and stroke incidence in a pooled study of five Scandinavian cohorts (NordSOUND). Methods: We pooled and harmonised data from five Scandinavian cohorts resulting in 78 389 participants. We obtained job data from national registries or questionnaires and recoded these to match a job-exposure matrix developed in Sweden, which specified the annual average daily noise exposure in five exposure classes (LAeq8h): &lt;70, 70-74, 75-79, 80-84, ≥85 dB(A). We identified residential address history and estimated 1-year average road traffic noise at baseline. Using national patient and mortality registers, we identified 7777 stroke cases with a median follow-up of 20.2 years. Analyses were conducted using Cox proportional hazards models adjusting for individual and area-level potential confounders. Results: Exposure to occupational noise at baseline was not associated with overall stroke in the fully adjusted models. For ischaemic stroke, occupational noise was associated with HRs (95% CI) of 1.08 (0.98 to 1.20), 1.09 (0.97 to 1.24) and 1.06 (0.92 to 1.21) in the 75-79, 80-84 and ≥85 dB(A) exposure groups, compared with &lt;70 dB(A), respectively. In subanalyses using time-varying occupational noise exposure, we observed an indication of higher stroke risk among the most exposed (≥85 dB(A)), particularly when restricting analyses to people exposed to occupational noise within the last year (HR: 1.27; 95% CI: 0.99 to 1.63). Conclusions: We found no association between occupational noise and risk of overall stroke after adjustment for confounders. However, the non-significantly increased risk of ischaemic stroke warrants further investigation. </p>}},
  author       = {{Thacher, Jesse D. and Roswall, Nina and Lissåker, Claudia and Aasvang, Gunn Marit and Albin, Maria and Andersson, Eva M. and Engström, Gunnar and Eriksson, Charlotta and Hvidtfeldt, Ulla Arthur and Ketzel, Matthias and Khan, Jibran and Lanki, Timo and Ljungman, Petter L.S. and Mattisson, Kristoffer and Molnar, Peter and Raaschou-Nielsen, Ole and Oudin, Anna and Overvad, Kim and Petersen, Sesilje Bondo and Pershagen, Göran and Poulsen, Aslak Harbo and Pyko, Andrei and Rizzuto, Debora and Rosengren, Annika and Schioler, Linus and Sjöström, Mattias and Stockfelt, Leo and Tiittanen, Pekka and Sallsten, Gerd and Ögren, Mikael and Selander, Jenny and Sorensen, Mette}},
  issn         = {{1351-0711}},
  keywords     = {{epidemiology; noise; public health}},
  language     = {{eng}},
  number       = {{9}},
  pages        = {{594--601}},
  publisher    = {{BMJ Publishing Group}},
  series       = {{Occupational and Environmental Medicine}},
  title        = {{Occupational noise exposure and risk of incident stroke : a pooled study of five Scandinavian cohorts}},
  url          = {{http://dx.doi.org/10.1136/oemed-2021-108053}},
  doi          = {{10.1136/oemed-2021-108053}},
  volume       = {{79}},
  year         = {{2022}},
}