High risk of tobacco-related cancers in CDKN2A mutation-positive melanoma families.
Helgadottir, Hildur ; Höiom, Veronica ; Jönsson, Göran B LU ; Tuominen, Rainer ; Ingvar, Christian LU ; Borg, Åke LU ; Olsson, Håkan LU
and Hansson, Johan
(2014)
In Journal of Medical Genetics
51(8).
p.545-552
- Abstract
- Germline mutations in the tumour suppressor gene CDKN2A occur in 5-20% of familial melanoma cases. A single founder mutation, p.Arg112dup, accounts for the majority of CDKN2A mutations in Swedish carriers. In a national program, carriers of p.Arg112dup mutation have been identified. The aim of this study was to assess cancer risks in p.Arg112dup carriers and their first degree relatives (FDRs) and second degree relatives (SDRs).
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4528376
- author
- Helgadottir, Hildur
; Höiom, Veronica
; Jönsson, Göran B
LU
; Tuominen, Rainer
; Ingvar, Christian
LU
; Borg, Åke
LU
; Olsson, Håkan
LU
and Hansson, Johan
- organization
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Medical Genetics
- volume
- 51
- issue
- 8
- pages
- 8 pages
- publisher
- BMJ Publishing Group
- external identifiers
-
- pmid:24935963
- wos:000339271200008
- scopus:84905579541
- pmid:24935963
- ISSN
- 0022-2593
- DOI
- 10.1136/jmedgenet-2014-102320
- language
- English
- LU publication?
- yes
- id
- 1f94fdee-d590-4ef0-88d1-8296d3f54b2c (old id 4528376)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/24935963?dopt=Abstract
- date added to LUP
- 2016-04-01 13:52:07
- date last changed
- 2022-01-27 21:32:47
@article{1f94fdee-d590-4ef0-88d1-8296d3f54b2c,
abstract = {{Germline mutations in the tumour suppressor gene CDKN2A occur in 5-20% of familial melanoma cases. A single founder mutation, p.Arg112dup, accounts for the majority of CDKN2A mutations in Swedish carriers. In a national program, carriers of p.Arg112dup mutation have been identified. The aim of this study was to assess cancer risks in p.Arg112dup carriers and their first degree relatives (FDRs) and second degree relatives (SDRs).}},
author = {{Helgadottir, Hildur and Höiom, Veronica and Jönsson, Göran B and Tuominen, Rainer and Ingvar, Christian and Borg, Åke and Olsson, Håkan and Hansson, Johan}},
issn = {{0022-2593}},
language = {{eng}},
number = {{8}},
pages = {{545--552}},
publisher = {{BMJ Publishing Group}},
series = {{Journal of Medical Genetics}},
title = {{High risk of tobacco-related cancers in CDKN2A mutation-positive melanoma families.}},
url = {{http://dx.doi.org/10.1136/jmedgenet-2014-102320}},
doi = {{10.1136/jmedgenet-2014-102320}},
volume = {{51}},
year = {{2014}},
}