CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells.
(2014) In BMC Medicine 12(1).- Abstract
- Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene lead to the disease cystic fibrosis (CF). Although patients with CF often have disturbances in glucose metabolism including impaired insulin release, no previous studies have tested the hypothesis that CFTR has a biological function in pancreatic beta-cells.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4529519
- author
- Edlund, Anna LU ; Esguerra, Jonathan LU ; Wendt, Anna LU ; Flodström-Tullberg, Malin and Eliasson, Lena LU
- organization
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- in
- BMC Medicine
- volume
- 12
- issue
- 1
- article number
- 87
- publisher
- BioMed Central (BMC)
- external identifiers
-
- pmid:24885604
- wos:000336683300001
- scopus:84901399700
- pmid:24885604
- ISSN
- 1741-7015
- DOI
- 10.1186/1741-7015-12-87
- language
- English
- LU publication?
- yes
- id
- dc862b1e-2b99-4a33-96f9-eeac0461095b (old id 4529519)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/24885604?dopt=Abstract
- date added to LUP
- 2016-04-01 12:58:26
- date last changed
- 2022-04-21 18:49:49
@article{dc862b1e-2b99-4a33-96f9-eeac0461095b, abstract = {{Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene lead to the disease cystic fibrosis (CF). Although patients with CF often have disturbances in glucose metabolism including impaired insulin release, no previous studies have tested the hypothesis that CFTR has a biological function in pancreatic beta-cells.}}, author = {{Edlund, Anna and Esguerra, Jonathan and Wendt, Anna and Flodström-Tullberg, Malin and Eliasson, Lena}}, issn = {{1741-7015}}, language = {{eng}}, number = {{1}}, publisher = {{BioMed Central (BMC)}}, series = {{BMC Medicine}}, title = {{CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells.}}, url = {{https://lup.lub.lu.se/search/files/3078280/5257216}}, doi = {{10.1186/1741-7015-12-87}}, volume = {{12}}, year = {{2014}}, }