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CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells.

Edlund, Anna LU ; Esguerra, Jonathan LU orcid ; Wendt, Anna LU ; Flodström-Tullberg, Malin and Eliasson, Lena LU orcid (2014) In BMC Medicine 12(1).
Abstract
Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene lead to the disease cystic fibrosis (CF). Although patients with CF often have disturbances in glucose metabolism including impaired insulin release, no previous studies have tested the hypothesis that CFTR has a biological function in pancreatic beta-cells.
Please use this url to cite or link to this publication:
author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
BMC Medicine
volume
12
issue
1
article number
87
publisher
BioMed Central (BMC)
external identifiers
  • pmid:24885604
  • wos:000336683300001
  • scopus:84901399700
  • pmid:24885604
ISSN
1741-7015
DOI
10.1186/1741-7015-12-87
language
English
LU publication?
yes
id
dc862b1e-2b99-4a33-96f9-eeac0461095b (old id 4529519)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24885604?dopt=Abstract
date added to LUP
2016-04-01 12:58:26
date last changed
2021-10-06 04:36:47
@article{dc862b1e-2b99-4a33-96f9-eeac0461095b,
  abstract     = {Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene lead to the disease cystic fibrosis (CF). Although patients with CF often have disturbances in glucose metabolism including impaired insulin release, no previous studies have tested the hypothesis that CFTR has a biological function in pancreatic beta-cells.},
  author       = {Edlund, Anna and Esguerra, Jonathan and Wendt, Anna and Flodström-Tullberg, Malin and Eliasson, Lena},
  issn         = {1741-7015},
  language     = {eng},
  number       = {1},
  publisher    = {BioMed Central (BMC)},
  series       = {BMC Medicine},
  title        = {CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells.},
  url          = {https://lup.lub.lu.se/search/files/3078280/5257216},
  doi          = {10.1186/1741-7015-12-87},
  volume       = {12},
  year         = {2014},
}