Chlamydial antibodies and risk of prostate cancer
(2005) In Cancer Epidemiology Biomarkers & Prevention 14(2). p.385-389- Abstract
- Objective: We assessed the risk of prostate cancer by exposure to Chlamydia trachomatis. Method: Seven hundred thirty eight cases of prostate cancer and 2,271 matched controls were identified from three serum sample banks in Finland, Norway, and Sweden by linkage to the population based cancer registries. Results: A statistically significant inverse association (odds ratio, 0.69; 95% confidence interval, 0.51-0.94) was found. It was consistent by different serotypes and there was a consistent dose-response relationship. Conclusion: C. trachomatis infection is not likely to increase the risk of prostate cancer. Whether the inverse relationship is true or due to difficulties in measuring the true exposure in prostatic tissue by serology,... (More)
- Objective: We assessed the risk of prostate cancer by exposure to Chlamydia trachomatis. Method: Seven hundred thirty eight cases of prostate cancer and 2,271 matched controls were identified from three serum sample banks in Finland, Norway, and Sweden by linkage to the population based cancer registries. Results: A statistically significant inverse association (odds ratio, 0.69; 95% confidence interval, 0.51-0.94) was found. It was consistent by different serotypes and there was a consistent dose-response relationship. Conclusion: C. trachomatis infection is not likely to increase the risk of prostate cancer. Whether the inverse relationship is true or due to difficulties in measuring the true exposure in prostatic tissue by serology, confounders or other sources of error remain open. (Less)
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https://lup.lub.lu.se/record/897421
- author
- organization
- publishing date
- 2005
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Cancer Epidemiology Biomarkers & Prevention
- volume
- 14
- issue
- 2
- pages
- 385 - 389
- publisher
- American Association for Cancer Research
- external identifiers
-
- wos:000227113800015
- pmid:15734962
- scopus:20944450872
- ISSN
- 1538-7755
- language
- English
- LU publication?
- yes
- id
- 454208c6-0b2a-4875-8a20-84ec10a20018 (old id 897421)
- alternative location
- http://cebp.aacrjournals.org/cgi/content/full/14/2/385
- date added to LUP
- 2016-04-01 16:50:30
- date last changed
- 2022-03-15 03:17:01
@article{454208c6-0b2a-4875-8a20-84ec10a20018, abstract = {{Objective: We assessed the risk of prostate cancer by exposure to Chlamydia trachomatis. Method: Seven hundred thirty eight cases of prostate cancer and 2,271 matched controls were identified from three serum sample banks in Finland, Norway, and Sweden by linkage to the population based cancer registries. Results: A statistically significant inverse association (odds ratio, 0.69; 95% confidence interval, 0.51-0.94) was found. It was consistent by different serotypes and there was a consistent dose-response relationship. Conclusion: C. trachomatis infection is not likely to increase the risk of prostate cancer. Whether the inverse relationship is true or due to difficulties in measuring the true exposure in prostatic tissue by serology, confounders or other sources of error remain open.}}, author = {{Anttila, T and Tenkanen, L and Lumme, S and Leinonen, M and Gislefoss, RE and Hallmans, G and Thoresen, S and Hakulinen, T and Luostarinen, T and Stattin, P and Saikku, P and Dillner, J and Lehtinen, M and Anttila, T and Tenkanen, L and Lumme, S and Leinonen, M and Gislefoss, RE and Hallmans, G and Thoresen, S and Hakulinen, T and Luostarinen, T and Stattin, P and Saikku, P and Dillner, Joakim and Lehtinen, M and Hakama, M}}, issn = {{1538-7755}}, language = {{eng}}, number = {{2}}, pages = {{385--389}}, publisher = {{American Association for Cancer Research}}, series = {{Cancer Epidemiology Biomarkers & Prevention}}, title = {{Chlamydial antibodies and risk of prostate cancer}}, url = {{http://cebp.aacrjournals.org/cgi/content/full/14/2/385}}, volume = {{14}}, year = {{2005}}, }