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Orthotopic Wilms tumor xenografts derived from cell lines reflect limited aspects of tumor morphology and clinical characteristics.

Holmquist Mengelbier, Linda LU ; Bexell, Daniel LU ; Sehic, Daniel LU ; Ciornei, Cristina LU and Gisselsson Nord, David LU (2014) In Pediatric Blood & Cancer 61(11). p.1949-1954
Abstract
Wilms tumor (WT) is a pediatric tumor of the kidney, the treatment of which includes heavy chemotherapy. Affected children would likely benefit from more targeted therapies with limited side effects. Establishment of relevant orthotopic WT xenografts is important to better understand mechanisms of WT growth and for preclinical drug testing.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Pediatric Blood & Cancer
volume
61
issue
11
pages
1949 - 1954
publisher
John Wiley and Sons Inc.
external identifiers
  • pmid:25044705
  • wos:000342723300008
  • scopus:84922678661
ISSN
1545-5017
DOI
10.1002/pbc.25131
language
English
LU publication?
yes
id
af40eeb1-49e3-49b3-ba2c-03d487d79ef7 (old id 4581636)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25044705?dopt=Abstract
date added to LUP
2014-08-08 21:25:40
date last changed
2017-01-01 03:20:25
@article{af40eeb1-49e3-49b3-ba2c-03d487d79ef7,
  abstract     = {Wilms tumor (WT) is a pediatric tumor of the kidney, the treatment of which includes heavy chemotherapy. Affected children would likely benefit from more targeted therapies with limited side effects. Establishment of relevant orthotopic WT xenografts is important to better understand mechanisms of WT growth and for preclinical drug testing.},
  author       = {Holmquist Mengelbier, Linda and Bexell, Daniel and Sehic, Daniel and Ciornei, Cristina and Gisselsson Nord, David},
  issn         = {1545-5017},
  language     = {eng},
  number       = {11},
  pages        = {1949--1954},
  publisher    = {John Wiley and Sons Inc.},
  series       = {Pediatric Blood & Cancer},
  title        = {Orthotopic Wilms tumor xenografts derived from cell lines reflect limited aspects of tumor morphology and clinical characteristics.},
  url          = {http://dx.doi.org/10.1002/pbc.25131},
  volume       = {61},
  year         = {2014},
}