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Risk of pediatric celiac disease according to HLA haplotype and country.

Liu, Edwin; Lee, Hye-Seung; Andrén Aronsson, Carin LU ; Hagopian, William A; Koletzko, Sibylle; Rewers, Marian J; Eisenbarth, George S; Bingley, Polly J; Bonifacio, Ezio and Simell, Ville, et al. (2014) In New England Journal of Medicine 371(1). p.42-49
Abstract
The presence of HLA haplotype DR3-DQ2 or DR4-DQ8 is associated with an increased risk of celiac disease. In addition, nearly all children with celiac disease have serum antibodies against tissue transglutaminase (tTG).
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keywords
Antibodies: blood, Autoimmune Diseases: epidemiology, Autoimmune Diseases: genetics, Celiac Disease: epidemiology, Celiac Disease: genetics, Europe: epidemiology, HLA-DQ Antigens: genetics, HLA-DR3 Antigen: genetics, HLA-DR4 Antigen: genetics, Transglutaminases: immunology, United States: epidemiology
in
New England Journal of Medicine
volume
371
issue
1
pages
42 - 49
publisher
Massachusetts Medical Society
external identifiers
  • pmid:24988556
  • wos:000338265700008
  • scopus:84903713927
ISSN
0028-4793
DOI
10.1056/NEJMoa1313977
language
English
LU publication?
yes
id
b9d491e4-2502-4241-8dcc-318b80632792 (old id 4583661)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/24988556?dopt=Abstract
date added to LUP
2014-08-06 22:58:15
date last changed
2017-11-05 03:08:45
@article{b9d491e4-2502-4241-8dcc-318b80632792,
  abstract     = {The presence of HLA haplotype DR3-DQ2 or DR4-DQ8 is associated with an increased risk of celiac disease. In addition, nearly all children with celiac disease have serum antibodies against tissue transglutaminase (tTG).},
  author       = {Liu, Edwin and Lee, Hye-Seung and Andrén Aronsson, Carin and Hagopian, William A and Koletzko, Sibylle and Rewers, Marian J and Eisenbarth, George S and Bingley, Polly J and Bonifacio, Ezio and Simell, Ville and Agardh, Daniel},
  issn         = {0028-4793},
  keyword      = {Antibodies: blood,Autoimmune Diseases: epidemiology,Autoimmune Diseases: genetics,Celiac Disease: epidemiology,Celiac Disease: genetics,Europe: epidemiology,HLA-DQ Antigens: genetics,HLA-DR3 Antigen: genetics,HLA-DR4 Antigen: genetics,Transglutaminases: immunology,United States: epidemiology},
  language     = {eng},
  number       = {1},
  pages        = {42--49},
  publisher    = {Massachusetts Medical Society},
  series       = {New England Journal of Medicine},
  title        = {Risk of pediatric celiac disease according to HLA haplotype and country.},
  url          = {http://dx.doi.org/10.1056/NEJMoa1313977},
  volume       = {371},
  year         = {2014},
}