Changes in the Urinary Sodium-to-Potassium Ratio Are Associated with Blood Pressure Change in Older Japanese Adults : A 7-Year Longitudinal Study
(2022) In Journal of Clinical Medicine 11(17).- Abstract
Studies on the association between sodium-to-potassium (Na/K) ratio changes and blood pressure (BP) changes among older adults are limited. This 7-year longitudinal study examined the association between Na/K ratio changes (evaluated using spot urine tests) and BP changes among older Japanese adults. Data were collected from 432 participants (mean age: 70.3±4.4; range: 65–84 years) in 2012 and 2019. Changes in BP and the Na/K ratio over 7 years were calculated by subtracting baseline values from values noted during a follow-up survey. The median systolic and diastolic BP (SBP) and (DBP) changes after 7 years were 4 (IQR, −7, 14) and −1 (IQR, −9, 5) mmHg, respectively. The median Na/K ratio was changed during the follow-up period by −0.2... (More)
Studies on the association between sodium-to-potassium (Na/K) ratio changes and blood pressure (BP) changes among older adults are limited. This 7-year longitudinal study examined the association between Na/K ratio changes (evaluated using spot urine tests) and BP changes among older Japanese adults. Data were collected from 432 participants (mean age: 70.3±4.4; range: 65–84 years) in 2012 and 2019. Changes in BP and the Na/K ratio over 7 years were calculated by subtracting baseline values from values noted during a follow-up survey. The median systolic and diastolic BP (SBP) and (DBP) changes after 7 years were 4 (IQR, −7, 14) and −1 (IQR, −9, 5) mmHg, respectively. The median Na/K ratio was changed during the follow-up period by −0.2 (IQR, −1.3, 0.7). A generalized linear model indicated that Na/K ratio changes were positively associated with SBP (B = 2.03, p < 0.001) and DBP (B = 0.62, p = 0.021) changes. In the non-antihypertensive medication-using group, urinary Na/K ratio changes were associated with SBP and DBP changes (B = 2.39, p = 0.001; B = 0.99, p = 0.033). In the antihypertensive medication user group, urinary Na/K ratio changes were associated with SBP changes (B = 1.62, p = 0.015). We confirmed the association between changes in the Na/K ratio and changes in BP.
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- author
- Abe, Takafumi ; Endo, Takeshi ; Hamano, Tsuyoshi ; Okuyama, Kenta LU and Yano, Shozo
- organization
- publishing date
- 2022-09
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- blood pressure changes, older adults, salt intake, sodium-to-potassium ratio
- in
- Journal of Clinical Medicine
- volume
- 11
- issue
- 17
- article number
- 5093
- publisher
- MDPI AG
- external identifiers
-
- pmid:36079021
- scopus:85137819019
- ISSN
- 2077-0383
- DOI
- 10.3390/jcm11175093
- language
- English
- LU publication?
- yes
- id
- 45ed676d-1201-4c98-89ac-52541606abe6
- date added to LUP
- 2022-12-02 13:41:43
- date last changed
- 2024-09-19 23:21:36
@article{45ed676d-1201-4c98-89ac-52541606abe6, abstract = {{<p>Studies on the association between sodium-to-potassium (Na/K) ratio changes and blood pressure (BP) changes among older adults are limited. This 7-year longitudinal study examined the association between Na/K ratio changes (evaluated using spot urine tests) and BP changes among older Japanese adults. Data were collected from 432 participants (mean age: 70.3±4.4; range: 65–84 years) in 2012 and 2019. Changes in BP and the Na/K ratio over 7 years were calculated by subtracting baseline values from values noted during a follow-up survey. The median systolic and diastolic BP (SBP) and (DBP) changes after 7 years were 4 (IQR, −7, 14) and −1 (IQR, −9, 5) mmHg, respectively. The median Na/K ratio was changed during the follow-up period by −0.2 (IQR, −1.3, 0.7). A generalized linear model indicated that Na/K ratio changes were positively associated with SBP (B = 2.03, p < 0.001) and DBP (B = 0.62, p = 0.021) changes. In the non-antihypertensive medication-using group, urinary Na/K ratio changes were associated with SBP and DBP changes (B = 2.39, p = 0.001; B = 0.99, p = 0.033). In the antihypertensive medication user group, urinary Na/K ratio changes were associated with SBP changes (B = 1.62, p = 0.015). We confirmed the association between changes in the Na/K ratio and changes in BP.</p>}}, author = {{Abe, Takafumi and Endo, Takeshi and Hamano, Tsuyoshi and Okuyama, Kenta and Yano, Shozo}}, issn = {{2077-0383}}, keywords = {{blood pressure changes; older adults; salt intake; sodium-to-potassium ratio}}, language = {{eng}}, number = {{17}}, publisher = {{MDPI AG}}, series = {{Journal of Clinical Medicine}}, title = {{Changes in the Urinary Sodium-to-Potassium Ratio Are Associated with Blood Pressure Change in Older Japanese Adults : A 7-Year Longitudinal Study}}, url = {{http://dx.doi.org/10.3390/jcm11175093}}, doi = {{10.3390/jcm11175093}}, volume = {{11}}, year = {{2022}}, }