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Changes in the Urinary Sodium-to-Potassium Ratio Are Associated with Blood Pressure Change in Older Japanese Adults : A 7-Year Longitudinal Study

Abe, Takafumi ; Endo, Takeshi ; Hamano, Tsuyoshi ; Okuyama, Kenta LU and Yano, Shozo (2022) In Journal of Clinical Medicine 11(17).
Abstract

Studies on the association between sodium-to-potassium (Na/K) ratio changes and blood pressure (BP) changes among older adults are limited. This 7-year longitudinal study examined the association between Na/K ratio changes (evaluated using spot urine tests) and BP changes among older Japanese adults. Data were collected from 432 participants (mean age: 70.3±4.4; range: 65–84 years) in 2012 and 2019. Changes in BP and the Na/K ratio over 7 years were calculated by subtracting baseline values from values noted during a follow-up survey. The median systolic and diastolic BP (SBP) and (DBP) changes after 7 years were 4 (IQR, −7, 14) and −1 (IQR, −9, 5) mmHg, respectively. The median Na/K ratio was changed during the follow-up period by −0.2... (More)

Studies on the association between sodium-to-potassium (Na/K) ratio changes and blood pressure (BP) changes among older adults are limited. This 7-year longitudinal study examined the association between Na/K ratio changes (evaluated using spot urine tests) and BP changes among older Japanese adults. Data were collected from 432 participants (mean age: 70.3±4.4; range: 65–84 years) in 2012 and 2019. Changes in BP and the Na/K ratio over 7 years were calculated by subtracting baseline values from values noted during a follow-up survey. The median systolic and diastolic BP (SBP) and (DBP) changes after 7 years were 4 (IQR, −7, 14) and −1 (IQR, −9, 5) mmHg, respectively. The median Na/K ratio was changed during the follow-up period by −0.2 (IQR, −1.3, 0.7). A generalized linear model indicated that Na/K ratio changes were positively associated with SBP (B = 2.03, p < 0.001) and DBP (B = 0.62, p = 0.021) changes. In the non-antihypertensive medication-using group, urinary Na/K ratio changes were associated with SBP and DBP changes (B = 2.39, p = 0.001; B = 0.99, p = 0.033). In the antihypertensive medication user group, urinary Na/K ratio changes were associated with SBP changes (B = 1.62, p = 0.015). We confirmed the association between changes in the Na/K ratio and changes in BP.

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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
blood pressure changes, older adults, salt intake, sodium-to-potassium ratio
in
Journal of Clinical Medicine
volume
11
issue
17
article number
5093
publisher
MDPI AG
external identifiers
  • scopus:85137819019
  • pmid:36079021
ISSN
2077-0383
DOI
10.3390/jcm11175093
language
English
LU publication?
yes
id
45ed676d-1201-4c98-89ac-52541606abe6
date added to LUP
2022-12-02 13:41:43
date last changed
2024-07-11 16:38:16
@article{45ed676d-1201-4c98-89ac-52541606abe6,
  abstract     = {{<p>Studies on the association between sodium-to-potassium (Na/K) ratio changes and blood pressure (BP) changes among older adults are limited. This 7-year longitudinal study examined the association between Na/K ratio changes (evaluated using spot urine tests) and BP changes among older Japanese adults. Data were collected from 432 participants (mean age: 70.3±4.4; range: 65–84 years) in 2012 and 2019. Changes in BP and the Na/K ratio over 7 years were calculated by subtracting baseline values from values noted during a follow-up survey. The median systolic and diastolic BP (SBP) and (DBP) changes after 7 years were 4 (IQR, −7, 14) and −1 (IQR, −9, 5) mmHg, respectively. The median Na/K ratio was changed during the follow-up period by −0.2 (IQR, −1.3, 0.7). A generalized linear model indicated that Na/K ratio changes were positively associated with SBP (B = 2.03, p &lt; 0.001) and DBP (B = 0.62, p = 0.021) changes. In the non-antihypertensive medication-using group, urinary Na/K ratio changes were associated with SBP and DBP changes (B = 2.39, p = 0.001; B = 0.99, p = 0.033). In the antihypertensive medication user group, urinary Na/K ratio changes were associated with SBP changes (B = 1.62, p = 0.015). We confirmed the association between changes in the Na/K ratio and changes in BP.</p>}},
  author       = {{Abe, Takafumi and Endo, Takeshi and Hamano, Tsuyoshi and Okuyama, Kenta and Yano, Shozo}},
  issn         = {{2077-0383}},
  keywords     = {{blood pressure changes; older adults; salt intake; sodium-to-potassium ratio}},
  language     = {{eng}},
  number       = {{17}},
  publisher    = {{MDPI AG}},
  series       = {{Journal of Clinical Medicine}},
  title        = {{Changes in the Urinary Sodium-to-Potassium Ratio Are Associated with Blood Pressure Change in Older Japanese Adults : A 7-Year Longitudinal Study}},
  url          = {{http://dx.doi.org/10.3390/jcm11175093}},
  doi          = {{10.3390/jcm11175093}},
  volume       = {{11}},
  year         = {{2022}},
}