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Bacterial Imprinting at Pickering Emulsion Interfaces.

Shen, Xiantao LU ; Svensson Bonde, Johan LU ; Kamra, Tripta LU ; Bülow, Leif LU ; Leo, Jack C; Linke, Dirk and Ye, Lei LU (2014) In Angewandte Chemie (International edition) 53(40). p.10687-10690
Abstract
The tendency of bacteria to assemble at oil-water interfaces can be utilized to create microbial recognition sites on the surface of polymer beads. In this work, two different groups of bacteria were first treated with acryloyl-functionalized chitosan and then used to stabilize an oil-in-water emulsion composed of cross-linking monomers that were dispersed in aqueous buffer. Polymerization of the oil phase followed by removal of the bacterial template resulted in well-defined polymer beads bearing bacterial imprints. Chemical passivation of chitosan and cell displacement assays indicate that the bacterial recognition on the polymer beads was dependent on the nature of the pre-polymer and the target bacteria. The functional materials for... (More)
The tendency of bacteria to assemble at oil-water interfaces can be utilized to create microbial recognition sites on the surface of polymer beads. In this work, two different groups of bacteria were first treated with acryloyl-functionalized chitosan and then used to stabilize an oil-in-water emulsion composed of cross-linking monomers that were dispersed in aqueous buffer. Polymerization of the oil phase followed by removal of the bacterial template resulted in well-defined polymer beads bearing bacterial imprints. Chemical passivation of chitosan and cell displacement assays indicate that the bacterial recognition on the polymer beads was dependent on the nature of the pre-polymer and the target bacteria. The functional materials for microbial recognition show great potential for constructing cell-cell communication networks, biosensors, and new platforms for testing antibiotic drugs. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Angewandte Chemie (International edition)
volume
53
issue
40
pages
10687 - 10690
publisher
John Wiley & Sons
external identifiers
  • pmid:25111359
  • wos:000342761500021
  • scopus:84926501342
ISSN
1521-3773
DOI
10.1002/anie.201406049
language
English
LU publication?
yes
id
dad489b3-135c-402d-9b77-e75c999693cf (old id 4614965)
date added to LUP
2014-09-12 16:39:56
date last changed
2017-11-05 03:22:31
@article{dad489b3-135c-402d-9b77-e75c999693cf,
  abstract     = {The tendency of bacteria to assemble at oil-water interfaces can be utilized to create microbial recognition sites on the surface of polymer beads. In this work, two different groups of bacteria were first treated with acryloyl-functionalized chitosan and then used to stabilize an oil-in-water emulsion composed of cross-linking monomers that were dispersed in aqueous buffer. Polymerization of the oil phase followed by removal of the bacterial template resulted in well-defined polymer beads bearing bacterial imprints. Chemical passivation of chitosan and cell displacement assays indicate that the bacterial recognition on the polymer beads was dependent on the nature of the pre-polymer and the target bacteria. The functional materials for microbial recognition show great potential for constructing cell-cell communication networks, biosensors, and new platforms for testing antibiotic drugs.},
  author       = {Shen, Xiantao and Svensson Bonde, Johan and Kamra, Tripta and Bülow, Leif and Leo, Jack C and Linke, Dirk and Ye, Lei},
  issn         = {1521-3773},
  language     = {eng},
  number       = {40},
  pages        = {10687--10690},
  publisher    = {John Wiley & Sons},
  series       = {Angewandte Chemie (International edition)},
  title        = {Bacterial Imprinting at Pickering Emulsion Interfaces.},
  url          = {http://dx.doi.org/10.1002/anie.201406049},
  volume       = {53},
  year         = {2014},
}