Anti- or pro-proliferation - Conditional options for TGF-α and cetuximab in head and neck squamous cell carcinoma.
(2015) In Oral Oncology 51(1). p.46-52- Abstract
- Cetuximab is an epidermal growth factor receptor (EGFR)-targeting drug that has shown effects in head and neck squamous cell carcinoma (HNSCC). The effects are, however, small and have mainly been proven in a subset of patients, and the cost-effectiveness has been questioned. For this reason, we need to know more about the basic mechanisms controlling the effect of EGFR signalling on tumour growth.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4690842
- author
- Ekblad, Lars LU ; Welinder, Charlotte LU ; Kjellén, Elisabeth LU ; Brun, Eva LU and Wennerberg, Johan LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Oral Oncology
- volume
- 51
- issue
- 1
- pages
- 46 - 52
- publisher
- Elsevier
- external identifiers
-
- pmid:25261297
- wos:000346210900010
- scopus:84920506782
- pmid:25261297
- ISSN
- 1879-0593
- DOI
- 10.1016/j.oraloncology.2014.08.019
- language
- English
- LU publication?
- yes
- id
- 3b36f772-9bc0-4d5b-b3ed-a61bb2cbda05 (old id 4690842)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/25261297?dopt=Abstract
- date added to LUP
- 2016-04-01 09:47:35
- date last changed
- 2022-01-25 08:47:37
@article{3b36f772-9bc0-4d5b-b3ed-a61bb2cbda05, abstract = {{Cetuximab is an epidermal growth factor receptor (EGFR)-targeting drug that has shown effects in head and neck squamous cell carcinoma (HNSCC). The effects are, however, small and have mainly been proven in a subset of patients, and the cost-effectiveness has been questioned. For this reason, we need to know more about the basic mechanisms controlling the effect of EGFR signalling on tumour growth.}}, author = {{Ekblad, Lars and Welinder, Charlotte and Kjellén, Elisabeth and Brun, Eva and Wennerberg, Johan}}, issn = {{1879-0593}}, language = {{eng}}, number = {{1}}, pages = {{46--52}}, publisher = {{Elsevier}}, series = {{Oral Oncology}}, title = {{Anti- or pro-proliferation - Conditional options for TGF-α and cetuximab in head and neck squamous cell carcinoma.}}, url = {{http://dx.doi.org/10.1016/j.oraloncology.2014.08.019}}, doi = {{10.1016/j.oraloncology.2014.08.019}}, volume = {{51}}, year = {{2015}}, }