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Anti- or pro-proliferation - Conditional options for TGF-α and cetuximab in head and neck squamous cell carcinoma.

Ekblad, Lars LU ; Welinder, Charlotte LU ; Kjellén, Elisabeth LU ; Brun, Eva LU and Wennerberg, Johan LU (2015) In Oral Oncology 51(1). p.46-52
Abstract
Cetuximab is an epidermal growth factor receptor (EGFR)-targeting drug that has shown effects in head and neck squamous cell carcinoma (HNSCC). The effects are, however, small and have mainly been proven in a subset of patients, and the cost-effectiveness has been questioned. For this reason, we need to know more about the basic mechanisms controlling the effect of EGFR signalling on tumour growth.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Oral Oncology
volume
51
issue
1
pages
46 - 52
publisher
Elsevier
external identifiers
  • pmid:25261297
  • wos:000346210900010
  • scopus:84920506782
ISSN
1879-0593
DOI
10.1016/j.oraloncology.2014.08.019
language
English
LU publication?
yes
id
3b36f772-9bc0-4d5b-b3ed-a61bb2cbda05 (old id 4690842)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25261297?dopt=Abstract
date added to LUP
2014-10-08 18:53:12
date last changed
2017-10-22 03:00:08
@article{3b36f772-9bc0-4d5b-b3ed-a61bb2cbda05,
  abstract     = {Cetuximab is an epidermal growth factor receptor (EGFR)-targeting drug that has shown effects in head and neck squamous cell carcinoma (HNSCC). The effects are, however, small and have mainly been proven in a subset of patients, and the cost-effectiveness has been questioned. For this reason, we need to know more about the basic mechanisms controlling the effect of EGFR signalling on tumour growth.},
  author       = {Ekblad, Lars and Welinder, Charlotte and Kjellén, Elisabeth and Brun, Eva and Wennerberg, Johan},
  issn         = {1879-0593},
  language     = {eng},
  number       = {1},
  pages        = {46--52},
  publisher    = {Elsevier},
  series       = {Oral Oncology},
  title        = {Anti- or pro-proliferation - Conditional options for TGF-α and cetuximab in head and neck squamous cell carcinoma.},
  url          = {http://dx.doi.org/10.1016/j.oraloncology.2014.08.019},
  volume       = {51},
  year         = {2015},
}