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Molecular recognition of nucleic acids by nucleolipid/dendrimer surface complexes.

Yanez, Marianna LU ; Berti, Debora ; Montis, Costanza ; Campbell, Richard A ; Clifton, Luke A ; Skoda, Maximilian W A ; Soltwedel, Olaf ; Baglioni, Piero and Nylander, Tommy LU (2014) In Soft Matter 10(42). p.8401-8405
Abstract
We show for the first time that 1,2-dilauroyl-sn-glycero-3-phosphatidyladenosine nucleolipid surface complexes with cationic poly(amidoamine) dendrimers can be used to selectively bind DNA including oligonucleotides. This molecular recognition has high potential for applications involving biomedical and bioanalytic devices as well as drug delivery systems based on nucleic acids.
Please use this url to cite or link to this publication:
author
; ; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Soft Matter
volume
10
issue
42
pages
8401 - 8405
publisher
Royal Society of Chemistry
external identifiers
  • pmid:25246334
  • wos:000343037600002
  • scopus:84924043635
  • pmid:25246334
ISSN
1744-6848
DOI
10.1039/c4sm01733a
language
English
LU publication?
yes
id
0b1f613a-9b40-4958-aba1-f74039ab699b (old id 4691064)
date added to LUP
2016-04-01 10:32:10
date last changed
2022-03-12 06:47:07
@article{0b1f613a-9b40-4958-aba1-f74039ab699b,
  abstract     = {{We show for the first time that 1,2-dilauroyl-sn-glycero-3-phosphatidyladenosine nucleolipid surface complexes with cationic poly(amidoamine) dendrimers can be used to selectively bind DNA including oligonucleotides. This molecular recognition has high potential for applications involving biomedical and bioanalytic devices as well as drug delivery systems based on nucleic acids.}},
  author       = {{Yanez, Marianna and Berti, Debora and Montis, Costanza and Campbell, Richard A and Clifton, Luke A and Skoda, Maximilian W A and Soltwedel, Olaf and Baglioni, Piero and Nylander, Tommy}},
  issn         = {{1744-6848}},
  language     = {{eng}},
  number       = {{42}},
  pages        = {{8401--8405}},
  publisher    = {{Royal Society of Chemistry}},
  series       = {{Soft Matter}},
  title        = {{Molecular recognition of nucleic acids by nucleolipid/dendrimer surface complexes.}},
  url          = {{http://dx.doi.org/10.1039/c4sm01733a}},
  doi          = {{10.1039/c4sm01733a}},
  volume       = {{10}},
  year         = {{2014}},
}