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Evidence for altered inflammatory and repair responses in symptomatic carotid plaques from elderly patients.

Grufman, Helena LU ; Schiopu, Alexandru LU ; Edsfeldt, Andreas LU ; Björkbacka, Harry LU ; Nitulescu, Mihaela LU ; Nilsson, Marie MN LU ; Persson, Ana LU ; Nilsson, Jan LU and Goncalves, Isabel LU (2014) In Atherosclerosis 237(1). p.177-182
Abstract
Most acute cardiovascular events are caused by rupture of an atherosclerotic plaque. The incidence of cardiovascular events increases with age and inflammation is generally considered to be the main cause of increased plaque vulnerability. However, the relationship between age and plaque inflammation has not yet been fully clarified. The aim of our study was to determine if age-dependent plaque vulnerability is associated with increased plaque inflammation.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Atherosclerosis
volume
237
issue
1
pages
177 - 182
publisher
Elsevier
external identifiers
  • pmid:25240113
  • wos:000345011300029
  • scopus:84907726913
ISSN
1879-1484
DOI
10.1016/j.atherosclerosis.2014.08.042
language
English
LU publication?
yes
id
336e40a0-c926-4115-9ae7-d77d3d0ed314 (old id 4691162)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25240113?dopt=Abstract
date added to LUP
2014-10-08 14:59:23
date last changed
2017-05-07 03:17:45
@article{336e40a0-c926-4115-9ae7-d77d3d0ed314,
  abstract     = {Most acute cardiovascular events are caused by rupture of an atherosclerotic plaque. The incidence of cardiovascular events increases with age and inflammation is generally considered to be the main cause of increased plaque vulnerability. However, the relationship between age and plaque inflammation has not yet been fully clarified. The aim of our study was to determine if age-dependent plaque vulnerability is associated with increased plaque inflammation.},
  author       = {Grufman, Helena and Schiopu, Alexandru and Edsfeldt, Andreas and Björkbacka, Harry and Nitulescu, Mihaela and Nilsson, Marie MN and Persson, Ana and Nilsson, Jan and Goncalves, Isabel},
  issn         = {1879-1484},
  language     = {eng},
  number       = {1},
  pages        = {177--182},
  publisher    = {Elsevier},
  series       = {Atherosclerosis},
  title        = {Evidence for altered inflammatory and repair responses in symptomatic carotid plaques from elderly patients.},
  url          = {http://dx.doi.org/10.1016/j.atherosclerosis.2014.08.042},
  volume       = {237},
  year         = {2014},
}