Erythropoietin suppresses the activation of pro-apoptotic genes in head and neck squamous cell carcinoma xenografts exposed to surgical trauma.
Lindgren, Gustaf LU ; Ekblad, Lars LU
; Vallon-Christersson, Johan
LU
; Kjellén, Elisabeth
LU
; Gebre-Medhin, Maria
LU
and Wennerberg, Johan
LU
(2014)
In BMC Cancer
14.
- Abstract
- Several studies on the use of erythropoietin (Epo) to treat anaemia in patients undergoing cancer treatment have shown adverse effects on tumour control and survival. Experimental studies indicate that this could be linked to an interaction with wound healing processes and not an effect on tumour cells per se. We have previously shown that erythropoietin in combination with surgical trauma stimulates tumour growth. In the present study, we investigated the effect of surgery and Epo on gene expression.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4692467
- author
- Lindgren, Gustaf
LU
; Ekblad, Lars
LU
; Vallon-Christersson, Johan
LU
; Kjellén, Elisabeth
LU
; Gebre-Medhin, Maria
LU
and Wennerberg, Johan
LU
- organization
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- in
- BMC Cancer
- volume
- 14
- article number
- 648
- publisher
- BioMed Central (BMC)
- external identifiers
-
- pmid:25182342
- wos:000341737500001
- scopus:84907387754
- ISSN
- 1471-2407
- DOI
- 10.1186/1471-2407-14-648
- project
- Local recurrences in head and neck cancer – etiology and prevention
- language
- English
- LU publication?
- yes
- id
- 9c1e8d29-8bf2-475e-a26a-5b43303c40ca (old id 4692467)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/25182342?dopt=Abstract
- date added to LUP
- 2016-04-01 13:55:33
- date last changed
- 2022-03-14 02:43:45
@article{9c1e8d29-8bf2-475e-a26a-5b43303c40ca,
abstract = {{Several studies on the use of erythropoietin (Epo) to treat anaemia in patients undergoing cancer treatment have shown adverse effects on tumour control and survival. Experimental studies indicate that this could be linked to an interaction with wound healing processes and not an effect on tumour cells per se. We have previously shown that erythropoietin in combination with surgical trauma stimulates tumour growth. In the present study, we investigated the effect of surgery and Epo on gene expression.}},
author = {{Lindgren, Gustaf and Ekblad, Lars and Vallon-Christersson, Johan and Kjellén, Elisabeth and Gebre-Medhin, Maria and Wennerberg, Johan}},
issn = {{1471-2407}},
language = {{eng}},
publisher = {{BioMed Central (BMC)}},
series = {{BMC Cancer}},
title = {{Erythropoietin suppresses the activation of pro-apoptotic genes in head and neck squamous cell carcinoma xenografts exposed to surgical trauma.}},
url = {{https://lup.lub.lu.se/search/files/3671301/5276944}},
doi = {{10.1186/1471-2407-14-648}},
volume = {{14}},
year = {{2014}},
}