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PXL01 in Sodium Hyaluronate for Improvement of Hand Recovery after Flexor Tendon Repair Surgery: Randomized Controlled Trial.

Wiig, Monica E ; Dahlin, Lars LU orcid ; Fridén, Jan ; Hagberg, Lars LU ; Larsen, Sören E ; Wiklund, Kerstin and Mahlapuu, Margit (2014) In PLoS ONE 9(10).
Abstract
Postoperative adhesions constitute a substantial clinical problem in hand surgery. Fexor tendon injury and repair result in adhesion formation around the tendon, which restricts the gliding function of the tendon, leading to decreased digit mobility and impaired hand recovery. This study evaluated the efficacy and safety of the peptide PXL01 in preventing adhesions, and correspondingly improving hand function, in flexor tendon repair surgery.
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author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
PLoS ONE
volume
9
issue
10
article number
e110735
publisher
Public Library of Science (PLoS)
external identifiers
  • pmid:25340801
  • wos:000343662800053
  • scopus:84908455961
  • pmid:25340801
ISSN
1932-6203
DOI
10.1371/journal.pone.0110735
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Hand Surgery Research Group (013241910), Reconstructive Surgery (013240300)
id
9db59d92-d89b-4439-8671-ffa4ac0d623e (old id 4733322)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25340801?dopt=Abstract
date added to LUP
2016-04-01 14:12:24
date last changed
2022-05-07 21:36:38
@article{9db59d92-d89b-4439-8671-ffa4ac0d623e,
  abstract     = {{Postoperative adhesions constitute a substantial clinical problem in hand surgery. Fexor tendon injury and repair result in adhesion formation around the tendon, which restricts the gliding function of the tendon, leading to decreased digit mobility and impaired hand recovery. This study evaluated the efficacy and safety of the peptide PXL01 in preventing adhesions, and correspondingly improving hand function, in flexor tendon repair surgery.}},
  author       = {{Wiig, Monica E and Dahlin, Lars and Fridén, Jan and Hagberg, Lars and Larsen, Sören E and Wiklund, Kerstin and Mahlapuu, Margit}},
  issn         = {{1932-6203}},
  language     = {{eng}},
  number       = {{10}},
  publisher    = {{Public Library of Science (PLoS)}},
  series       = {{PLoS ONE}},
  title        = {{PXL01 in Sodium Hyaluronate for Improvement of Hand Recovery after Flexor Tendon Repair Surgery: Randomized Controlled Trial.}},
  url          = {{https://lup.lub.lu.se/search/files/3843122/7525885}},
  doi          = {{10.1371/journal.pone.0110735}},
  volume       = {{9}},
  year         = {{2014}},
}