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Lactose intolerance and risk of lung, breast and ovarian cancers: aetiological clues from a population-based study in Sweden.

Ji, Jianguang LU ; Sundquist, Jan LU and Sundquist, Kristina LU (2015) In British Journal of Cancer 112(1). p.149-152
Abstract
Background:Individuals with lactose intolerance are recommended to avoid milk or dairy products, which may affect the development of cancer.Methods:We identified individuals with lactose intolerance from several Swedish Registers linked to the Swedish Cancer Registry to calculate standardised incidence ratios (SIRs) for cancers in the breast, lung, and ovary.Results:A total of 22 788 individuals with lactose intolerance were identified, and their risks of lung (SIR=0.55), breast (SIR=0.79), and ovarian (SIR=0.61) cancers were significantly decreased. Cancer incidences in the siblings and parents of individuals with lactose intolerance were similar to those in the general population.Conclusions:In this large cohort study, people with... (More)
Background:Individuals with lactose intolerance are recommended to avoid milk or dairy products, which may affect the development of cancer.Methods:We identified individuals with lactose intolerance from several Swedish Registers linked to the Swedish Cancer Registry to calculate standardised incidence ratios (SIRs) for cancers in the breast, lung, and ovary.Results:A total of 22 788 individuals with lactose intolerance were identified, and their risks of lung (SIR=0.55), breast (SIR=0.79), and ovarian (SIR=0.61) cancers were significantly decreased. Cancer incidences in the siblings and parents of individuals with lactose intolerance were similar to those in the general population.Conclusions:In this large cohort study, people with lactose intolerance, characterised by low consumption of milk and other dairy products, had decreased risks of lung, breast, and ovarian cancers, but the decreased risks were not found in their family members, suggesting that the protective effects against these cancers may be related to their specific dietary pattern.British Journal of Cancer advance online publication, 14 October 2014; doi:10.1038/bjc.2014.544 www.bjcancer.com. (Less)
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author
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type
Contribution to journal
publication status
published
subject
in
British Journal of Cancer
volume
112
issue
1
pages
149 - 152
publisher
Nature Publishing Group
external identifiers
  • pmid:25314053
  • wos:000348280900021
  • scopus:84920658497
ISSN
1532-1827
DOI
10.1038/bjc.2014.544
language
English
LU publication?
yes
id
939382d5-aa65-48e1-b492-68ab02516223 (old id 4736949)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25314053?dopt=Abstract
date added to LUP
2014-11-08 23:32:48
date last changed
2017-11-12 03:14:25
@article{939382d5-aa65-48e1-b492-68ab02516223,
  abstract     = {Background:Individuals with lactose intolerance are recommended to avoid milk or dairy products, which may affect the development of cancer.Methods:We identified individuals with lactose intolerance from several Swedish Registers linked to the Swedish Cancer Registry to calculate standardised incidence ratios (SIRs) for cancers in the breast, lung, and ovary.Results:A total of 22 788 individuals with lactose intolerance were identified, and their risks of lung (SIR=0.55), breast (SIR=0.79), and ovarian (SIR=0.61) cancers were significantly decreased. Cancer incidences in the siblings and parents of individuals with lactose intolerance were similar to those in the general population.Conclusions:In this large cohort study, people with lactose intolerance, characterised by low consumption of milk and other dairy products, had decreased risks of lung, breast, and ovarian cancers, but the decreased risks were not found in their family members, suggesting that the protective effects against these cancers may be related to their specific dietary pattern.British Journal of Cancer advance online publication, 14 October 2014; doi:10.1038/bjc.2014.544 www.bjcancer.com.},
  author       = {Ji, Jianguang and Sundquist, Jan and Sundquist, Kristina},
  issn         = {1532-1827},
  language     = {eng},
  number       = {1},
  pages        = {149--152},
  publisher    = {Nature Publishing Group},
  series       = {British Journal of Cancer},
  title        = {Lactose intolerance and risk of lung, breast and ovarian cancers: aetiological clues from a population-based study in Sweden.},
  url          = {http://dx.doi.org/10.1038/bjc.2014.544},
  volume       = {112},
  year         = {2015},
}