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Incident urothelial cancer in the Malmö Diet and Cancer Study: cohort characteristics and further validation of ezrin as a prognostic biomarker.

Wennersten, Christoffer; Andersson, Gustav LU ; Boman, Karolina LU ; Nodin, Björn LU ; Gaber, Alexander LU and Jirström, Karin LU (2014) In Diagnostic Pathology 9(1).
Abstract
Reduced membranous expression of the cytoskeleton-associated protein ezrin has previously been demonstrated to correlate with poor prognosis in urothelial bladder cancer in several independent studies. The present study provides a first description of clinicopathological characteristics of incident urothelial cancers, not only located to the bladder, in the prospective, population-based cohort study Malmö Diet and Cancer. In addition, the prognostic value of ezrin expression is validated in primary tumours, and the longitudinal expression of ezrin examined in a subset of primary and recurrent tumours (n = 28).
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Diagnostic Pathology
volume
9
issue
1
publisher
BioMed Central
external identifiers
  • pmid:25278252
  • wos:000343803700001
  • scopus:84907960550
ISSN
1746-1596
DOI
10.1186/s13000-014-0189-5
language
English
LU publication?
yes
id
7f6c9d7c-0827-4876-8287-a6ffb5fcdb17 (old id 4738454)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25278252?dopt=Abstract
date added to LUP
2014-11-05 19:09:19
date last changed
2017-03-10 15:41:00
@article{7f6c9d7c-0827-4876-8287-a6ffb5fcdb17,
  abstract     = {Reduced membranous expression of the cytoskeleton-associated protein ezrin has previously been demonstrated to correlate with poor prognosis in urothelial bladder cancer in several independent studies. The present study provides a first description of clinicopathological characteristics of incident urothelial cancers, not only located to the bladder, in the prospective, population-based cohort study Malmö Diet and Cancer. In addition, the prognostic value of ezrin expression is validated in primary tumours, and the longitudinal expression of ezrin examined in a subset of primary and recurrent tumours (n = 28).},
  articleno    = {189},
  author       = {Wennersten, Christoffer and Andersson, Gustav and Boman, Karolina and Nodin, Björn and Gaber, Alexander and Jirström, Karin},
  issn         = {1746-1596},
  language     = {eng},
  number       = {1},
  publisher    = {BioMed Central},
  series       = {Diagnostic Pathology},
  title        = {Incident urothelial cancer in the Malmö Diet and Cancer Study: cohort characteristics and further validation of ezrin as a prognostic biomarker.},
  url          = {http://dx.doi.org/10.1186/s13000-014-0189-5},
  volume       = {9},
  year         = {2014},
}