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Characterizing motor and non-motor aspects of early-morning off periods in Parkinson's disease: An international multicenter study.

Rizos, A; Martinez-Martin, P; Odin, Per LU ; Antonini, A; Kessel, B; Kozul, T Klemencic; Todorova, A; Douiri, A; Martin, A and Stocchi, F, et al. (2014) In Parkinsonism & Related Disorders 20(11). p.1231-1235
Abstract
The characteristic off periods that develop over time in subjects with Parkinson's disease (PD) on chronic levodopa therapy are usually considered to be motor complications but more recently the important contribution of non-motor off and non-motor fluctuations has also been acknowledged. Early-morning off (EMO) periods in PD patients are known to be a cause of significant disability, in addition to having a negative impact on quality of life. Yet EMOs are poorly defined, particularly in relation to non-motor symptoms (NMS).
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type
Contribution to journal
publication status
published
subject
in
Parkinsonism & Related Disorders
volume
20
issue
11
pages
1231 - 1235
publisher
Elsevier
external identifiers
  • pmid:25269446
  • wos:000345483000023
  • scopus:84908644276
ISSN
1873-5126
DOI
10.1016/j.parkreldis.2014.09.013
language
English
LU publication?
yes
id
058e21ca-92f4-4597-b16b-0fde4b24f450 (old id 4738703)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25269446?dopt=Abstract
date added to LUP
2014-11-04 18:50:12
date last changed
2017-10-22 03:15:31
@article{058e21ca-92f4-4597-b16b-0fde4b24f450,
  abstract     = {The characteristic off periods that develop over time in subjects with Parkinson's disease (PD) on chronic levodopa therapy are usually considered to be motor complications but more recently the important contribution of non-motor off and non-motor fluctuations has also been acknowledged. Early-morning off (EMO) periods in PD patients are known to be a cause of significant disability, in addition to having a negative impact on quality of life. Yet EMOs are poorly defined, particularly in relation to non-motor symptoms (NMS).},
  author       = {Rizos, A and Martinez-Martin, P and Odin, Per and Antonini, A and Kessel, B and Kozul, T Klemencic and Todorova, A and Douiri, A and Martin, A and Stocchi, F and Dietrichs, E and Chaudhuri, K Ray},
  issn         = {1873-5126},
  language     = {eng},
  number       = {11},
  pages        = {1231--1235},
  publisher    = {Elsevier},
  series       = {Parkinsonism & Related Disorders},
  title        = {Characterizing motor and non-motor aspects of early-morning off periods in Parkinson's disease: An international multicenter study.},
  url          = {http://dx.doi.org/10.1016/j.parkreldis.2014.09.013},
  volume       = {20},
  year         = {2014},
}