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Telomere-associated repeats in Chironomus form discrete subfamilies generated by gene conversion

Cohn, Marita LU and Edström, Jan-Erik LU (1992) In Journal of Molecular Evolution 35(2). p.114-122
Abstract
In dipteran insects the most distal telomere-associated DNA known to exist consists of long, complex tandem repeats. We have classified the 340-bp tandemly arranged repeats in Chironomus pallidivittatus. The repeats are distributed in a small number of subfamilies. One type of the repeat has the character of a master unit from which other main units can be derived usually by simple changes. The derived subfamilies contain segments that are degenerate versions of the corresponding segment in the master sequence. Such segments can also occur together in one and the same repeat unit in different combinations. There is a complete absence of subfamily-specific base variants in regions lying outside of the degenerate segments. Homogenization... (More)
In dipteran insects the most distal telomere-associated DNA known to exist consists of long, complex tandem repeats. We have classified the 340-bp tandemly arranged repeats in Chironomus pallidivittatus. The repeats are distributed in a small number of subfamilies. One type of the repeat has the character of a master unit from which other main units can be derived usually by simple changes. The derived subfamilies contain segments that are degenerate versions of the corresponding segment in the master sequence. Such segments can also occur together in one and the same repeat unit in different combinations. There is a complete absence of subfamily-specific base variants in regions lying outside of the degenerate segments. Homogenization takes place between DNA sequences that are often smaller than a whole repeat unit. The mosaic structure of the repeat arrays suggests that gene conversion is an important force in the generation and maintenance of this family of repeats. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Molecular Evolution
volume
35
issue
2
pages
114 - 122
publisher
Springer
external identifiers
  • scopus:0026760180
ISSN
0022-2844
DOI
10.1007/BF00183222
language
English
LU publication?
yes
id
fd4e50dd-db8f-4885-bb4b-3c428fc7261e (old id 4742846)
date added to LUP
2014-11-06 11:36:29
date last changed
2017-01-01 04:34:51
@article{fd4e50dd-db8f-4885-bb4b-3c428fc7261e,
  abstract     = {In dipteran insects the most distal telomere-associated DNA known to exist consists of long, complex tandem repeats. We have classified the 340-bp tandemly arranged repeats in Chironomus pallidivittatus. The repeats are distributed in a small number of subfamilies. One type of the repeat has the character of a master unit from which other main units can be derived usually by simple changes. The derived subfamilies contain segments that are degenerate versions of the corresponding segment in the master sequence. Such segments can also occur together in one and the same repeat unit in different combinations. There is a complete absence of subfamily-specific base variants in regions lying outside of the degenerate segments. Homogenization takes place between DNA sequences that are often smaller than a whole repeat unit. The mosaic structure of the repeat arrays suggests that gene conversion is an important force in the generation and maintenance of this family of repeats.},
  author       = {Cohn, Marita and Edström, Jan-Erik},
  issn         = {0022-2844},
  language     = {eng},
  number       = {2},
  pages        = {114--122},
  publisher    = {Springer},
  series       = {Journal of Molecular Evolution},
  title        = {Telomere-associated repeats in Chironomus form discrete subfamilies generated by gene conversion},
  url          = {http://dx.doi.org/10.1007/BF00183222},
  volume       = {35},
  year         = {1992},
}