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Likelihood of acute coronary syndrome in emergency department chest pain patients varies with time of presentation

Ekelund, Ulf LU ; Akbarzadeh, Mahin LU ; Khoshnood, Ardavan LU ; Björk, Jonas LU and Ohlsson, Mattias LU (2012) In BMC Research Notes 5(Article nr. 420).
Abstract
Background: There is a circadian and circaseptal (weekly) variation in the onset of acute coronary syndrome (ACS). The aim of this study was to elucidate whether the likelihood of ACS among emergency department (ED) chest pain patients varies with the time of presentation.



Methods: All patients presenting to the Lund ED at Skåne University Hospital with chest pain or discomfort during 2006 and 2007 were retrospectively included. Age, sex, arrival time at the ED and discharge diagnose (ACS or not) were obtained from the electronic medical records.



Results: There was a clear but moderate circadian variation in the likelihood of ACS among presenting chest pain patients, the likelihood between 8 and 10 am... (More)
Background: There is a circadian and circaseptal (weekly) variation in the onset of acute coronary syndrome (ACS). The aim of this study was to elucidate whether the likelihood of ACS among emergency department (ED) chest pain patients varies with the time of presentation.



Methods: All patients presenting to the Lund ED at Skåne University Hospital with chest pain or discomfort during 2006 and 2007 were retrospectively included. Age, sex, arrival time at the ED and discharge diagnose (ACS or not) were obtained from the electronic medical records.



Results: There was a clear but moderate circadian variation in the likelihood of ACS among presenting chest pain patients, the likelihood between 8 and 10 am being almost twice as high as between 6 and 8 pm. This was mainly explained by a variation in the ACS likelihood in females and patients under 65 years, with no significant variation in males and patients over 65 years. There was no significant circaseptal variation in the ACS likelihood.



Conclusions: Our results indicate that there is a circadian variation in the likelihood of ACS among ED chest pain patients, and suggest that physicians should consider the time of presentation to the ED when determining the likelihood of ACS. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Acute Coronary Syndrome, Chest pain, Sex differences
in
BMC Research Notes
volume
5
issue
Article nr. 420
publisher
BioMed Central
external identifiers
  • scopus:84864555326
ISSN
1756-0500
DOI
10.1186/1756-0500-5-420
language
English
LU publication?
yes
id
a3bed8cd-41bd-4360-8230-0f7528eaf69f (old id 4814410)
date added to LUP
2016-01-27 14:22:46
date last changed
2017-01-01 07:49:59
@article{a3bed8cd-41bd-4360-8230-0f7528eaf69f,
  abstract     = {Background: There is a circadian and circaseptal (weekly) variation in the onset of acute coronary syndrome (ACS). The aim of this study was to elucidate whether the likelihood of ACS among emergency department (ED) chest pain patients varies with the time of presentation.<br/><br>
<br/><br>
Methods: All patients presenting to the Lund ED at Skåne University Hospital with chest pain or discomfort during 2006 and 2007 were retrospectively included. Age, sex, arrival time at the ED and discharge diagnose (ACS or not) were obtained from the electronic medical records.<br/><br>
<br/><br>
Results: There was a clear but moderate circadian variation in the likelihood of ACS among presenting chest pain patients, the likelihood between 8 and 10 am being almost twice as high as between 6 and 8 pm. This was mainly explained by a variation in the ACS likelihood in females and patients under 65 years, with no significant variation in males and patients over 65 years. There was no significant circaseptal variation in the ACS likelihood.<br/><br>
<br/><br>
Conclusions: Our results indicate that there is a circadian variation in the likelihood of ACS among ED chest pain patients, and suggest that physicians should consider the time of presentation to the ED when determining the likelihood of ACS.},
  author       = {Ekelund, Ulf and Akbarzadeh, Mahin and Khoshnood, Ardavan and Björk, Jonas and Ohlsson, Mattias},
  issn         = {1756-0500},
  keyword      = {Acute Coronary Syndrome,Chest pain,Sex differences},
  language     = {eng},
  number       = {Article nr. 420},
  publisher    = {BioMed Central},
  series       = {BMC Research Notes},
  title        = {Likelihood of acute coronary syndrome in emergency department chest pain patients varies with time of presentation},
  url          = {http://dx.doi.org/10.1186/1756-0500-5-420},
  volume       = {5},
  year         = {2012},
}