Individually tailored exercise in patients with postural orthostatic tachycardia syndrome related to post-COVID-19 condition - a feasibility study
Svensson, Annie ; Svensson-Raskh, Anna ; Holmström, Linda ; Hallberg, Carl ; Bezuidenhout, Lucian ; Moulaee Conradsson, David ; Ståhlberg, Marcus ; Bruchfeld, Judith ; Fedorowski, Artur LU
and Nygren-Bonnier, Malin
(2024)
In Scientific Reports
14.
p.1-14
- Abstract
Postural orthostatic tachycardia syndrome (POTS) occurs in approximately 30% of people with highly symptomatic post-COVID-19 condition (PCC). It involves several symptoms that limit physical and psychological functions and cause reduced quality of life. Evidence for different treatments of POTS and PCC is limited, and this study aimed to evaluate the feasibility of individually tailored physical exercise. The secondary aim of the study was to evaluate the preliminary effectiveness of this intervention. Twenty-six participants (81% female, median age 41 years) were enrolled and performed individually tailored endurance and strength training, with progression, for twelve weeks. During the intervention period, the participants had weekly... (More)
Postural orthostatic tachycardia syndrome (POTS) occurs in approximately 30% of people with highly symptomatic post-COVID-19 condition (PCC). It involves several symptoms that limit physical and psychological functions and cause reduced quality of life. Evidence for different treatments of POTS and PCC is limited, and this study aimed to evaluate the feasibility of individually tailored physical exercise. The secondary aim of the study was to evaluate the preliminary effectiveness of this intervention. Twenty-six participants (81% female, median age 41 years) were enrolled and performed individually tailored endurance and strength training, with progression, for twelve weeks. During the intervention period, the participants had weekly support from a physiotherapist. Feasibility was evaluated with good compliance, with 76% adherence to exercise prescription and 96% completing the study protocol. The treatment was safe, and the evaluation methods (questionnaires, physical assessments, and accelerometer monitoring) were judged to be feasible. After the intervention, improvements in symptom burden as well as in psychological and physical functions were observed. In conclusion, future randomized controlled trials can be performed with only minor adjustments and could include questionnaires, physical assessment and accelerometer monitoring, which were demonstrated as feasible by this study.
(Less)
- author
- Svensson, Annie
; Svensson-Raskh, Anna
; Holmström, Linda
; Hallberg, Carl
; Bezuidenhout, Lucian
; Moulaee Conradsson, David
; Ståhlberg, Marcus
; Bruchfeld, Judith
; Fedorowski, Artur
LU
and Nygren-Bonnier, Malin
- publishing date
- 2024-08-28
- type
- Contribution to journal
- publication status
- published
- keywords
- Humans, Postural Orthostatic Tachycardia Syndrome/therapy, Female, Male, COVID-19/complications, Feasibility Studies, Adult, Exercise Therapy/methods, Middle Aged, Quality of Life, Post-Acute COVID-19 Syndrome, Exercise, SARS-CoV-2/isolation & purification, Resistance Training/methods, Surveys and Questionnaires
- in
- Scientific Reports
- volume
- 14
- article number
- 20017
- pages
- 1 - 14
- publisher
- Nature Publishing Group
- external identifiers
-
- pmid:39198662
- ISSN
- 2045-2322
- DOI
- 10.1038/s41598-024-71055-5
- language
- English
- LU publication?
- no
- additional info
- © 2024. The Author(s).
- id
- 48e820a0-e7ea-4dc8-b4f5-8ba4e5bd30ed
- date added to LUP
- 2024-09-02 20:56:21
- date last changed
- 2024-09-03 08:27:37
@article{48e820a0-e7ea-4dc8-b4f5-8ba4e5bd30ed,
abstract = {{<p>Postural orthostatic tachycardia syndrome (POTS) occurs in approximately 30% of people with highly symptomatic post-COVID-19 condition (PCC). It involves several symptoms that limit physical and psychological functions and cause reduced quality of life. Evidence for different treatments of POTS and PCC is limited, and this study aimed to evaluate the feasibility of individually tailored physical exercise. The secondary aim of the study was to evaluate the preliminary effectiveness of this intervention. Twenty-six participants (81% female, median age 41 years) were enrolled and performed individually tailored endurance and strength training, with progression, for twelve weeks. During the intervention period, the participants had weekly support from a physiotherapist. Feasibility was evaluated with good compliance, with 76% adherence to exercise prescription and 96% completing the study protocol. The treatment was safe, and the evaluation methods (questionnaires, physical assessments, and accelerometer monitoring) were judged to be feasible. After the intervention, improvements in symptom burden as well as in psychological and physical functions were observed. In conclusion, future randomized controlled trials can be performed with only minor adjustments and could include questionnaires, physical assessment and accelerometer monitoring, which were demonstrated as feasible by this study.</p>}},
author = {{Svensson, Annie and Svensson-Raskh, Anna and Holmström, Linda and Hallberg, Carl and Bezuidenhout, Lucian and Moulaee Conradsson, David and Ståhlberg, Marcus and Bruchfeld, Judith and Fedorowski, Artur and Nygren-Bonnier, Malin}},
issn = {{2045-2322}},
keywords = {{Humans; Postural Orthostatic Tachycardia Syndrome/therapy; Female; Male; COVID-19/complications; Feasibility Studies; Adult; Exercise Therapy/methods; Middle Aged; Quality of Life; Post-Acute COVID-19 Syndrome; Exercise; SARS-CoV-2/isolation & purification; Resistance Training/methods; Surveys and Questionnaires}},
language = {{eng}},
month = {{08}},
pages = {{1--14}},
publisher = {{Nature Publishing Group}},
series = {{Scientific Reports}},
title = {{Individually tailored exercise in patients with postural orthostatic tachycardia syndrome related to post-COVID-19 condition - a feasibility study}},
url = {{http://dx.doi.org/10.1038/s41598-024-71055-5}},
doi = {{10.1038/s41598-024-71055-5}},
volume = {{14}},
year = {{2024}},
}